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Evaluation of non-modified wireframe DNA origami for acute toxicity and biodistribution in mice

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Wireframe DNA origami can be used to fabricate virus-like particles for a range of biomedical applications, including the delivery of nucleic acid therapeutics. However, the acute toxicity and biodistribution of these wireframe nucleic acid nanoparticles (NANPs) have not previously been characterize...

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Detalles Bibliográficos
Autores principales:	Wamhoff, Eike-Christian, Knappe, Grant A., Burds, Aurora A., Du, Rebecca R., Neun, Barry W., Difilippantonio, Simone, Sanders, Chelsea, Edmondson, Elijah F., Matta, Jennifer L., Dobrovolskaia, Marina A., Bathe, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002694/ https://www.ncbi.nlm.nih.gov/pubmed/36909507 http://dx.doi.org/10.1101/2023.02.25.530026

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