Elucidating Molecular Mechanisms of Protoxin-2 State-specific Binding to the Human Na(V)1.7 Channel

Human voltage-gated sodium (hNa(V)) channels are responsible for initiating and propagating action potentials in excitable cells and mutations have been associated with numerous cardiac and neurological disorders. hNa(V)1.7 channels are expressed in peripheral neurons and are promising targets for p...

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Detalles Bibliográficos
Autores principales: Ngo, Khoa, Mateos, Diego Lopez, Han, Yanxiao, Rouen, Kyle C., Ahn, Surl-Hee, Wulff, Heike, Clancy, Colleen E., Yarov-Yarovoy, Vladimir, Vorobyov, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002706/
https://www.ncbi.nlm.nih.gov/pubmed/36909474
http://dx.doi.org/10.1101/2023.02.27.530360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002706/
https://www.ncbi.nlm.nih.gov/pubmed/36909474
http://dx.doi.org/10.1101/2023.02.27.530360

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