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Elucidating Molecular Mechanisms of Protoxin-2 State-specific Binding to the Human Na(V)1.7 Channel
Human voltage-gated sodium (hNa(V)) channels are responsible for initiating and propagating action potentials in excitable cells and mutations have been associated with numerous cardiac and neurological disorders. hNa(V)1.7 channels are expressed in peripheral neurons and are promising targets for p...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002706/ https://www.ncbi.nlm.nih.gov/pubmed/36909474 http://dx.doi.org/10.1101/2023.02.27.530360 |