PAI-1 regulates AT2-mediated re-alveolarization and ion permeability

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BACKGROUND: Acute lung injury is characterized by overwhelmingly elevated PAI-1 in both lung edema fluid and the circulating system. The role of increased PAI-1, encoded by Serpine1 gene, in the regeneration of injured lung epithelium has not been understood completely. This study aimed to investiga...

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Detalles Bibliográficos
Autores principales: Ali, Gibran, Zhang, Mo, Chang, Jianjun, Zhao, Runzhen, Jin, Yang, Ji, Hong-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002791/
https://www.ncbi.nlm.nih.gov/pubmed/36909505
http://dx.doi.org/10.21203/rs.3.rs-2289657/v1
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