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PPARα and PPARγ are expressed in midbrain dopamine neurons and modulate dopamine- and cannabinoid-mediated behavior in mice

Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear receptors that regulate gene expression. Δ(9)-tetrahydrocannabinol (Δ(9)-THC) is a PPARg agonist and some endocannabinoids are natural activators of PPARa and PPARg. Therefore, both the receptors are putative cannabinoid rec...

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Detalles Bibliográficos
Autores principales: Xi, Zheng-Xiong, Hempel, Briana, Crissman, Madeline, Pari, Sruti, Klein, Benjamin, Bi, Guo-Hua, Alton, Hannah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002816/
https://www.ncbi.nlm.nih.gov/pubmed/36909477
http://dx.doi.org/10.21203/rs.3.rs-2614714/v1