Tdrd3-null mice show post-transcriptional and behavioral impairments associated with neurogenesis and synaptic plasticity

The Topoisomerase 3B (Top3b) - Tudor domain containing 3 (Tdrd3) protein complex is the only dual-activity topoisomerase complex in animals that can alter the topology of both DNA and RNA. TOP3B mutations in humans are associated with schizophrenia, autism and cognitive disorders; and Top3b-null mic...

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Detalles Bibliográficos
Autores principales: Zhu, XingLiang, Joo, Yuyoung, Bossi, Simone, McDevitt, Ross, Xie, Aoji, Wang, Yue, Xue, Yutong, Su, Shuaikun, Lee, Seung Kyu, Sah, Nirnath, Zhang, Shiliang, Ye, Rong, Pinto, Alejandro, Zhang, Yongqing, Araki, Kimi, Araki, Masatake, Morales, Marisela, Mattson, Mark, van Praag, Henriette, Wang, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002826/
https://www.ncbi.nlm.nih.gov/pubmed/36909584
http://dx.doi.org/10.21203/rs.3.rs-2597043/v1

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