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Fibroblast, Epithelial and Endothelial Cell-Derived Human Cytomegalovirus Strains Display Distinct Neutralizing Antibody Responses and Varying Levels of gH/gL Complexes

In sequential sera from pregnant women with HCMV primary infection (PI), the serum neutralizing activity is higher against virions produced in epithelial and endothelial cells than in fibroblasts. Immunoblotting shows that the pentamer complex/trimer complex (PC/TC) ratio varies according to the pro...

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Detalles Bibliográficos
Autores principales:	Fornara, Chiara, Schultz, Eric, Lilleri, Daniele, Baldanti, Fausto, Ryckman, Brent, Gerna, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003051/ https://www.ncbi.nlm.nih.gov/pubmed/36901847 http://dx.doi.org/10.3390/ijms24054417

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