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Integrating genome-wide association study with regulatory SNP annotations identified novel candidate genes for osteoporosis

AIMS: Osteoporosis (OP) is a metabolic bone disease, characterized by a decrease in bone mineral density (BMD). However, the research of regulatory variants has been limited for BMD. In this study, we aimed to explore novel regulatory genetic variants associated with BMD. METHODS: We conducted an in...

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Detalles Bibliográficos
Autores principales: Jia, Yumeng, Qi, Xin, Ma, Mei, Cheng, Shiqiang, Cheng, Bolun, Liang, Chujun, Guo, Xiong, Zhang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003063/
https://www.ncbi.nlm.nih.gov/pubmed/37051837
http://dx.doi.org/10.1302/2046-3758.122.BJR-2022-0206.R1