Cargando…
VRK1 Kinase Activity Modulating Histone H4K16 Acetylation Inhibited by SIRT2 and VRK-IN-1
The accessibility of DNA to different cellular functions requires a dynamic regulation of chromatin organization that is mediated by different epigenetic modifications, which regulate chromatin accessibility and degree of compaction. These epigenetic modifications, particularly the acetylation of hi...
Autores principales: | Monte-Serrano, Eva, Lazo, Pedro A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003087/ https://www.ncbi.nlm.nih.gov/pubmed/36902348 http://dx.doi.org/10.3390/ijms24054912 |
Ejemplares similares
-
The pattern of histone H3 epigenetic posttranslational modifications is regulated by the VRK1 chromatin kinase
por: Monte-Serrano, Eva, et al.
Publicado: (2023) -
Differential Inhibitor Sensitivity between Human Kinases VRK1 and VRK2
por: Vázquez-Cedeira, Marta, et al.
Publicado: (2011) -
Proteomics Identification of Nuclear Ran GTPase as an Inhibitor of Human VRK1 and VRK2 (Vaccinia-related Kinase) Activities
por: Sanz-García, Marta, et al.
Publicado: (2008) -
VRK1 Phosphorylates Tip60/KAT5 and Is Required for H4K16 Acetylation in Response to DNA Damage
por: García-González, Raúl, et al.
Publicado: (2020) -
VRK1 functional insufficiency due to alterations in protein stability or kinase activity of human VRK1 pathogenic variants implicated in neuromotor syndromes
por: Martín-Doncel, Elena, et al.
Publicado: (2019)