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Altered Storage and Function of von Willebrand Factor in Human Cardiac Microvascular Endothelial Cells Isolated from Recipient Transplant Hearts

The assembly of von Willebrand factor (VWF) into ordered helical tubules within endothelial Weibel–Palade bodies (WPBs) is required for the efficient deployment of the protein at sites of vascular injury. VWF trafficking and storage are sensitive to cellular and environmental stresses that are assoc...

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Detalles Bibliográficos
Autores principales: Meli, Athinoula, McCormack, Ann, Conte, Ianina, Chen, Qu, Streetley, James, Rose, Marlene L., Bierings, Ruben, Hannah, Matthew J., Molloy, Justin E., Rosenthal, Peter B., Carter, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003102/
https://www.ncbi.nlm.nih.gov/pubmed/36901985
http://dx.doi.org/10.3390/ijms24054553