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Predictive Value of Prognostic Nutritional Index for Early Postoperative Mobility in Elderly Patients with Pertrochanteric Fracture Treated with Intramedullary Nail Osteosynthesis

Background: Early postoperative mobilization is essential for orthogeriatric patients. The prognostic nutritional index (PNI) is widely used to evaluate nutritional status. This study sought to investigate the predictive value of PNI for early postoperative mobility in patients with pertrochanteric...

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Autores principales: Faust, Leon Marcel, Lerchenberger, Maximilian, Gleich, Johannes, Linhart, Christoph, Keppler, Alexander Martin, Schmidmaier, Ralf, Böcker, Wolfgang, Neuerburg, Carl, Zhang, Yunjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003114/
https://www.ncbi.nlm.nih.gov/pubmed/36902579
http://dx.doi.org/10.3390/jcm12051792
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author Faust, Leon Marcel
Lerchenberger, Maximilian
Gleich, Johannes
Linhart, Christoph
Keppler, Alexander Martin
Schmidmaier, Ralf
Böcker, Wolfgang
Neuerburg, Carl
Zhang, Yunjie
author_facet Faust, Leon Marcel
Lerchenberger, Maximilian
Gleich, Johannes
Linhart, Christoph
Keppler, Alexander Martin
Schmidmaier, Ralf
Böcker, Wolfgang
Neuerburg, Carl
Zhang, Yunjie
author_sort Faust, Leon Marcel
collection PubMed
description Background: Early postoperative mobilization is essential for orthogeriatric patients. The prognostic nutritional index (PNI) is widely used to evaluate nutritional status. This study sought to investigate the predictive value of PNI for early postoperative mobility in patients with pertrochanteric femur fractures. Materials and methods: This study included 156 geriatric patients with pertrochanteric femur fractures treated with TFN-Advance™ (DePuy Synthes, Raynham, MA, USA). Mobility was evaluated on the third postoperative day and by discharge. Stepwise logistic regression analyses were performed to evaluate the association significance of PNI with postoperative mobility together with comorbidities. The optimal PNI cut-off value for mobility was analyzed using the receiver operating characteristic (ROC) curve. Results: Three days postoperatively, PNI was an independent predictor of mobility (OR: 1.14, 95% CI: 1.07–1.23, p < 0.01). By discharge, it was found that PNI (OR: 1.18, 95% CI: 1.08–1.30, p < 0.01) and dementia (OR: 0.17, 95% CI: 0.07–0.40, p < 0.001) were significant predictors. PNI correlated weakly with age (r = −0.27, p < 0.001). The PNI cut-off value for mobility on the third postoperative day was 38.1 (specificity = 78.5%, sensitivity = 63.6%). Conclusions: Our findings indicate that PNI is an independent predictor of early postoperative mobility in geriatric patients with pertrochanteric femur fractures treated with TFNA™.
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spelling pubmed-100031142023-03-11 Predictive Value of Prognostic Nutritional Index for Early Postoperative Mobility in Elderly Patients with Pertrochanteric Fracture Treated with Intramedullary Nail Osteosynthesis Faust, Leon Marcel Lerchenberger, Maximilian Gleich, Johannes Linhart, Christoph Keppler, Alexander Martin Schmidmaier, Ralf Böcker, Wolfgang Neuerburg, Carl Zhang, Yunjie J Clin Med Article Background: Early postoperative mobilization is essential for orthogeriatric patients. The prognostic nutritional index (PNI) is widely used to evaluate nutritional status. This study sought to investigate the predictive value of PNI for early postoperative mobility in patients with pertrochanteric femur fractures. Materials and methods: This study included 156 geriatric patients with pertrochanteric femur fractures treated with TFN-Advance™ (DePuy Synthes, Raynham, MA, USA). Mobility was evaluated on the third postoperative day and by discharge. Stepwise logistic regression analyses were performed to evaluate the association significance of PNI with postoperative mobility together with comorbidities. The optimal PNI cut-off value for mobility was analyzed using the receiver operating characteristic (ROC) curve. Results: Three days postoperatively, PNI was an independent predictor of mobility (OR: 1.14, 95% CI: 1.07–1.23, p < 0.01). By discharge, it was found that PNI (OR: 1.18, 95% CI: 1.08–1.30, p < 0.01) and dementia (OR: 0.17, 95% CI: 0.07–0.40, p < 0.001) were significant predictors. PNI correlated weakly with age (r = −0.27, p < 0.001). The PNI cut-off value for mobility on the third postoperative day was 38.1 (specificity = 78.5%, sensitivity = 63.6%). Conclusions: Our findings indicate that PNI is an independent predictor of early postoperative mobility in geriatric patients with pertrochanteric femur fractures treated with TFNA™. MDPI 2023-02-23 /pmc/articles/PMC10003114/ /pubmed/36902579 http://dx.doi.org/10.3390/jcm12051792 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Faust, Leon Marcel
Lerchenberger, Maximilian
Gleich, Johannes
Linhart, Christoph
Keppler, Alexander Martin
Schmidmaier, Ralf
Böcker, Wolfgang
Neuerburg, Carl
Zhang, Yunjie
Predictive Value of Prognostic Nutritional Index for Early Postoperative Mobility in Elderly Patients with Pertrochanteric Fracture Treated with Intramedullary Nail Osteosynthesis
title Predictive Value of Prognostic Nutritional Index for Early Postoperative Mobility in Elderly Patients with Pertrochanteric Fracture Treated with Intramedullary Nail Osteosynthesis
title_full Predictive Value of Prognostic Nutritional Index for Early Postoperative Mobility in Elderly Patients with Pertrochanteric Fracture Treated with Intramedullary Nail Osteosynthesis
title_fullStr Predictive Value of Prognostic Nutritional Index for Early Postoperative Mobility in Elderly Patients with Pertrochanteric Fracture Treated with Intramedullary Nail Osteosynthesis
title_full_unstemmed Predictive Value of Prognostic Nutritional Index for Early Postoperative Mobility in Elderly Patients with Pertrochanteric Fracture Treated with Intramedullary Nail Osteosynthesis
title_short Predictive Value of Prognostic Nutritional Index for Early Postoperative Mobility in Elderly Patients with Pertrochanteric Fracture Treated with Intramedullary Nail Osteosynthesis
title_sort predictive value of prognostic nutritional index for early postoperative mobility in elderly patients with pertrochanteric fracture treated with intramedullary nail osteosynthesis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003114/
https://www.ncbi.nlm.nih.gov/pubmed/36902579
http://dx.doi.org/10.3390/jcm12051792
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