Cargando…
Predictive Value of Prognostic Nutritional Index for Early Postoperative Mobility in Elderly Patients with Pertrochanteric Fracture Treated with Intramedullary Nail Osteosynthesis
Background: Early postoperative mobilization is essential for orthogeriatric patients. The prognostic nutritional index (PNI) is widely used to evaluate nutritional status. This study sought to investigate the predictive value of PNI for early postoperative mobility in patients with pertrochanteric...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003114/ https://www.ncbi.nlm.nih.gov/pubmed/36902579 http://dx.doi.org/10.3390/jcm12051792 |
_version_ | 1784904533909962752 |
---|---|
author | Faust, Leon Marcel Lerchenberger, Maximilian Gleich, Johannes Linhart, Christoph Keppler, Alexander Martin Schmidmaier, Ralf Böcker, Wolfgang Neuerburg, Carl Zhang, Yunjie |
author_facet | Faust, Leon Marcel Lerchenberger, Maximilian Gleich, Johannes Linhart, Christoph Keppler, Alexander Martin Schmidmaier, Ralf Böcker, Wolfgang Neuerburg, Carl Zhang, Yunjie |
author_sort | Faust, Leon Marcel |
collection | PubMed |
description | Background: Early postoperative mobilization is essential for orthogeriatric patients. The prognostic nutritional index (PNI) is widely used to evaluate nutritional status. This study sought to investigate the predictive value of PNI for early postoperative mobility in patients with pertrochanteric femur fractures. Materials and methods: This study included 156 geriatric patients with pertrochanteric femur fractures treated with TFN-Advance™ (DePuy Synthes, Raynham, MA, USA). Mobility was evaluated on the third postoperative day and by discharge. Stepwise logistic regression analyses were performed to evaluate the association significance of PNI with postoperative mobility together with comorbidities. The optimal PNI cut-off value for mobility was analyzed using the receiver operating characteristic (ROC) curve. Results: Three days postoperatively, PNI was an independent predictor of mobility (OR: 1.14, 95% CI: 1.07–1.23, p < 0.01). By discharge, it was found that PNI (OR: 1.18, 95% CI: 1.08–1.30, p < 0.01) and dementia (OR: 0.17, 95% CI: 0.07–0.40, p < 0.001) were significant predictors. PNI correlated weakly with age (r = −0.27, p < 0.001). The PNI cut-off value for mobility on the third postoperative day was 38.1 (specificity = 78.5%, sensitivity = 63.6%). Conclusions: Our findings indicate that PNI is an independent predictor of early postoperative mobility in geriatric patients with pertrochanteric femur fractures treated with TFNA™. |
format | Online Article Text |
id | pubmed-10003114 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100031142023-03-11 Predictive Value of Prognostic Nutritional Index for Early Postoperative Mobility in Elderly Patients with Pertrochanteric Fracture Treated with Intramedullary Nail Osteosynthesis Faust, Leon Marcel Lerchenberger, Maximilian Gleich, Johannes Linhart, Christoph Keppler, Alexander Martin Schmidmaier, Ralf Böcker, Wolfgang Neuerburg, Carl Zhang, Yunjie J Clin Med Article Background: Early postoperative mobilization is essential for orthogeriatric patients. The prognostic nutritional index (PNI) is widely used to evaluate nutritional status. This study sought to investigate the predictive value of PNI for early postoperative mobility in patients with pertrochanteric femur fractures. Materials and methods: This study included 156 geriatric patients with pertrochanteric femur fractures treated with TFN-Advance™ (DePuy Synthes, Raynham, MA, USA). Mobility was evaluated on the third postoperative day and by discharge. Stepwise logistic regression analyses were performed to evaluate the association significance of PNI with postoperative mobility together with comorbidities. The optimal PNI cut-off value for mobility was analyzed using the receiver operating characteristic (ROC) curve. Results: Three days postoperatively, PNI was an independent predictor of mobility (OR: 1.14, 95% CI: 1.07–1.23, p < 0.01). By discharge, it was found that PNI (OR: 1.18, 95% CI: 1.08–1.30, p < 0.01) and dementia (OR: 0.17, 95% CI: 0.07–0.40, p < 0.001) were significant predictors. PNI correlated weakly with age (r = −0.27, p < 0.001). The PNI cut-off value for mobility on the third postoperative day was 38.1 (specificity = 78.5%, sensitivity = 63.6%). Conclusions: Our findings indicate that PNI is an independent predictor of early postoperative mobility in geriatric patients with pertrochanteric femur fractures treated with TFNA™. MDPI 2023-02-23 /pmc/articles/PMC10003114/ /pubmed/36902579 http://dx.doi.org/10.3390/jcm12051792 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Faust, Leon Marcel Lerchenberger, Maximilian Gleich, Johannes Linhart, Christoph Keppler, Alexander Martin Schmidmaier, Ralf Böcker, Wolfgang Neuerburg, Carl Zhang, Yunjie Predictive Value of Prognostic Nutritional Index for Early Postoperative Mobility in Elderly Patients with Pertrochanteric Fracture Treated with Intramedullary Nail Osteosynthesis |
title | Predictive Value of Prognostic Nutritional Index for Early Postoperative Mobility in Elderly Patients with Pertrochanteric Fracture Treated with Intramedullary Nail Osteosynthesis |
title_full | Predictive Value of Prognostic Nutritional Index for Early Postoperative Mobility in Elderly Patients with Pertrochanteric Fracture Treated with Intramedullary Nail Osteosynthesis |
title_fullStr | Predictive Value of Prognostic Nutritional Index for Early Postoperative Mobility in Elderly Patients with Pertrochanteric Fracture Treated with Intramedullary Nail Osteosynthesis |
title_full_unstemmed | Predictive Value of Prognostic Nutritional Index for Early Postoperative Mobility in Elderly Patients with Pertrochanteric Fracture Treated with Intramedullary Nail Osteosynthesis |
title_short | Predictive Value of Prognostic Nutritional Index for Early Postoperative Mobility in Elderly Patients with Pertrochanteric Fracture Treated with Intramedullary Nail Osteosynthesis |
title_sort | predictive value of prognostic nutritional index for early postoperative mobility in elderly patients with pertrochanteric fracture treated with intramedullary nail osteosynthesis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003114/ https://www.ncbi.nlm.nih.gov/pubmed/36902579 http://dx.doi.org/10.3390/jcm12051792 |
work_keys_str_mv | AT faustleonmarcel predictivevalueofprognosticnutritionalindexforearlypostoperativemobilityinelderlypatientswithpertrochantericfracturetreatedwithintramedullarynailosteosynthesis AT lerchenbergermaximilian predictivevalueofprognosticnutritionalindexforearlypostoperativemobilityinelderlypatientswithpertrochantericfracturetreatedwithintramedullarynailosteosynthesis AT gleichjohannes predictivevalueofprognosticnutritionalindexforearlypostoperativemobilityinelderlypatientswithpertrochantericfracturetreatedwithintramedullarynailosteosynthesis AT linhartchristoph predictivevalueofprognosticnutritionalindexforearlypostoperativemobilityinelderlypatientswithpertrochantericfracturetreatedwithintramedullarynailosteosynthesis AT keppleralexandermartin predictivevalueofprognosticnutritionalindexforearlypostoperativemobilityinelderlypatientswithpertrochantericfracturetreatedwithintramedullarynailosteosynthesis AT schmidmaierralf predictivevalueofprognosticnutritionalindexforearlypostoperativemobilityinelderlypatientswithpertrochantericfracturetreatedwithintramedullarynailosteosynthesis AT bockerwolfgang predictivevalueofprognosticnutritionalindexforearlypostoperativemobilityinelderlypatientswithpertrochantericfracturetreatedwithintramedullarynailosteosynthesis AT neuerburgcarl predictivevalueofprognosticnutritionalindexforearlypostoperativemobilityinelderlypatientswithpertrochantericfracturetreatedwithintramedullarynailosteosynthesis AT zhangyunjie predictivevalueofprognosticnutritionalindexforearlypostoperativemobilityinelderlypatientswithpertrochantericfracturetreatedwithintramedullarynailosteosynthesis |