Prevention of Ventriculostomy Related Infection: Effectiveness of Impregnated Biomaterial

External ventricular drain(EVD) exposes the patient to infectious complications which are associated with significant morbidity and economic burden. Biomaterials impregnated with various antimicrobial agents have been developed to decrease the rate of bacterial colonization and subsequent infection....

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Detalles Bibliográficos
Autores principales: Diop, Sylvain, Roujansky, Ariane, Kallel, Hatem, Mounier, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003160/
https://www.ncbi.nlm.nih.gov/pubmed/36902247
http://dx.doi.org/10.3390/ijms24054819
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author Diop, Sylvain
Roujansky, Ariane
Kallel, Hatem
Mounier, Roman
author_facet Diop, Sylvain
Roujansky, Ariane
Kallel, Hatem
Mounier, Roman
author_sort Diop, Sylvain
collection PubMed
description External ventricular drain(EVD) exposes the patient to infectious complications which are associated with significant morbidity and economic burden. Biomaterials impregnated with various antimicrobial agents have been developed to decrease the rate of bacterial colonization and subsequent infection. While promising, antibiotics and silver-impregnated EVD showed conflicting clinical results. The aim of the present review is to discuss the challenges associated with the development of antimicrobial EVD catheters and their effectiveness from the bench to the bedside.
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spelling pubmed-100031602023-03-11 Prevention of Ventriculostomy Related Infection: Effectiveness of Impregnated Biomaterial Diop, Sylvain Roujansky, Ariane Kallel, Hatem Mounier, Roman Int J Mol Sci Review External ventricular drain(EVD) exposes the patient to infectious complications which are associated with significant morbidity and economic burden. Biomaterials impregnated with various antimicrobial agents have been developed to decrease the rate of bacterial colonization and subsequent infection. While promising, antibiotics and silver-impregnated EVD showed conflicting clinical results. The aim of the present review is to discuss the challenges associated with the development of antimicrobial EVD catheters and their effectiveness from the bench to the bedside. MDPI 2023-03-02 /pmc/articles/PMC10003160/ /pubmed/36902247 http://dx.doi.org/10.3390/ijms24054819 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Diop, Sylvain
Roujansky, Ariane
Kallel, Hatem
Mounier, Roman
Prevention of Ventriculostomy Related Infection: Effectiveness of Impregnated Biomaterial
title Prevention of Ventriculostomy Related Infection: Effectiveness of Impregnated Biomaterial
title_full Prevention of Ventriculostomy Related Infection: Effectiveness of Impregnated Biomaterial
title_fullStr Prevention of Ventriculostomy Related Infection: Effectiveness of Impregnated Biomaterial
title_full_unstemmed Prevention of Ventriculostomy Related Infection: Effectiveness of Impregnated Biomaterial
title_short Prevention of Ventriculostomy Related Infection: Effectiveness of Impregnated Biomaterial
title_sort prevention of ventriculostomy related infection: effectiveness of impregnated biomaterial
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003160/
https://www.ncbi.nlm.nih.gov/pubmed/36902247
http://dx.doi.org/10.3390/ijms24054819
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