Intracellular Helix-Loop-Helix Domain Modulates Inactivation Kinetics of Mammalian TRPV5 and TRPV6 Channels

TRPV5 and TRPV6 are calcium-selective ion channels expressed at the apical membrane of epithelial cells. Important for systemic calcium (Ca(2+)) homeostasis, these channels are considered gatekeepers of this cation transcellular transport. Intracellular Ca(2+) exerts a negative control over the acti...

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Detalles Bibliográficos
Autores principales: Flores-Aldama, Lisandra, Bustos, Daniel, Cabezas-Bratesco, Deny, Gonzalez, Wendy, Brauchi, Sebastian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003196/
https://www.ncbi.nlm.nih.gov/pubmed/36901904
http://dx.doi.org/10.3390/ijms24054470

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