Cargando…

Proteomics- and Metabolomics-Based Analysis of Metabolic Changes in a Swine Model of Pulmonary Hypertension

Pulmonary vein stenosis (PVS) causes a rare type of pulmonary hypertension (PH) by impacting the flow and pressure within the pulmonary vasculature, resulting in endothelial dysfunction and metabolic changes. A prudent line of treatment in this type of PH would be targeted therapy to relieve the pre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sen, Payel, Shashikadze, Bachuki, Flenkenthaler, Florian, Van de Kamp, Esther, Tian, Siyu, Meng, Chen, Gigl, Michael, Fröhlich, Thomas, Merkus, Daphne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003314/ https://www.ncbi.nlm.nih.gov/pubmed/36902298 http://dx.doi.org/10.3390/ijms24054870

Ejemplares similares

Developmental Effects of (Pre-)Gestational Diabetes on Offspring: Systematic Screening Using Omics Approaches
por: Shashikadze, Bachuki, et al.
Publicado: (2021)

Proteomics and disease network associations evaluation of environmentally relevant Bisphenol A concentrations in a human 3D neural stem cell model
por: Horánszky, Alex, et al.
Publicado: (2023)

Differential Effects of Insulin-Deficient Diabetes Mellitus on Visceral vs. Subcutaneous Adipose Tissue—Multi-omics Insights From the Munich MIDY Pig Model
por: Flenkenthaler, Florian, et al.
Publicado: (2021)

Cardiac remodelling in a swine model of chronic thromboembolic pulmonary hypertension: comparison of right vs. left ventricle
por: Stam, Kelly, et al.
Publicado: (2019)

Transition from post‐capillary pulmonary hypertension to combined pre‐ and post‐capillary pulmonary hypertension in swine: a key role for endothelin
por: van Duin, Richard W. B., et al.
Publicado: (2018)

Purinergic Dysfunction in Pulmonary Arterial Hypertension
por: Cai, Zongye, et al.
Publicado: (2020)

Changes in the nitric oxide pathway of the pulmonary vasculature after exposure to hypoxia in swine model of neonatal pulmonary vascular disease
por: de Wijs‐Meijler, Daphne P. M., et al.
Publicado: (2018)

Impaired pulmonary vasomotor control in exercising swine with multiple comorbidities
por: van de Wouw, Jens, et al.
Publicado: (2021)

Age-Related Alterations in the Testicular Proteome of a Non-Human Primate
por: Stöckl, Jan B., et al.
Publicado: (2021)

Proteomic Insights into Senescence of Testicular Peritubular Cells from a Nonhuman Primate Model
por: Stöckl, Jan B., et al.
Publicado: (2020)

Chronic Thromboembolic Pulmonary Hypertension – What Have We Learned From Large Animal Models
por: Stam, Kelly, et al.
Publicado: (2021)

Alterations in vasomotor control of coronary resistance vessels in remodelled myocardium of swine with a recent myocardial infarction
por: Duncker, Dirk J., et al.
Publicado: (2008)

Proteomic and Metabolomic Analyses of Right Ventricular Failure due to Pulmonary Arterial Hypertension
por: Qin, Xiaohan, et al.
Publicado: (2022)

Exercise and hypoxia unmask pulmonary vascular disease and right ventricular dysfunction in a 10‐ to 12‐week‐old swine model of neonatal oxidative injury
por: Steenhorst, Jarno J., et al.
Publicado: (2022)

Progressive Proteome Changes in the Myocardium of a Pig Model for Duchenne Muscular Dystrophy
por: Tamiyakul, Hathaichanok, et al.
Publicado: (2020)

Time course of VCAM-1 expression in reperfused myocardial infarction in swine and its relation to retention of intracoronary administered bone marrow-derived mononuclear cells
por: Uitterdijk, André, et al.
Publicado: (2017)

Intervening with the Nitric Oxide Pathway to Alleviate Pulmonary Hypertension in Pulmonary Vein Stenosis
por: van Duin, Richard W. B., et al.
Publicado: (2019)

Lower Plasma Melatonin Levels Predict Worse Long-Term Survival in Pulmonary Arterial Hypertension
por: Cai, Zongye, et al.
Publicado: (2020)

Progressive muscle proteome changes in a clinically relevant pig model of Duchenne muscular dystrophy
por: Fröhlich, Thomas, et al.
Publicado: (2016)

Maternal hyperglycemia induces alterations in hepatic amino acid, glucose and lipid metabolism of neonatal offspring: Multi-omics insights from a diabetic pig model
por: Shashikadze, Bachuki, et al.
Publicado: (2023)

Metabolomic Heterogeneity of Pulmonary Arterial Hypertension
por: Zhao, Yidan, et al.
Publicado: (2014)

Uridine Adenosine Tetraphosphate-Induced Coronary Relaxation Is Blunted in Swine With Pressure Overload: A Role for Vasoconstrictor Prostanoids
por: Zhou, Zhichao, et al.
Publicado: (2018)

Systemic deletion of DMD exon 51 rescues clinically severe Duchenne muscular dystrophy in a pig model lacking DMD exon 52
por: Stirm, Michael, et al.
Publicado: (2023)

Proteomics to Metabolomics: A New Insight into the Pathogenesis of Hypertensive Nephropathy
por: Eshraghi, Yasin, et al.
Publicado: (2023)

An explorative metabolomic analysis of the endothelium in pulmonary hypertension
por: Carlsen, J., et al.
Publicado: (2022)

Altered purinergic signaling in uridine adenosine tetraphosphate-induced coronary relaxation in swine with metabolic derangement
por: Zhou, Zhichao, et al.
Publicado: (2017)

Proteomic analysis of pulmonary arterial hypertension
por: Qin, Xiaohan, et al.
Publicado: (2021)

Validation of 4D flow CMR against simultaneous invasive hemodynamic measurements: a swine study
por: Stam, Kelly, et al.
Publicado: (2019)

Left ventricular remodeling in swine after myocardial infarction: a transcriptional genomics approach
por: Kuster, Diederik W. D., et al.
Publicado: (2011)

Plasma metabolomic profile in chronic thromboembolic pulmonary hypertension
por: Heresi, Gustavo A., et al.
Publicado: (2020)

Myocardial proteomic profile in pulmonary arterial hypertension
por: Hołda, Mateusz K., et al.
Publicado: (2020)

Integrative proteomics and phosphoproteomics in pulmonary arterial hypertension
por: Xu, Weiling, et al.
Publicado: (2019)

Transcatheter radiofrequency pulmonary artery denervation in swine: the evaluation of lesion degree, hemodynamics and pulmonary hypertension inducibility
por: Goncharova, Natalia S., et al.
Publicado: (2021)

Kynurenine metabolites predict survival in pulmonary arterial hypertension: A role for IL-6/IL-6Rα
por: Cai, Zongye, et al.
Publicado: (2022)

Microenvironmental Regulation of Macrophage Transcriptomic and Metabolomic Profiles in Pulmonary Hypertension
por: Li, Min, et al.
Publicado: (2021)

Deriving Convergent and Divergent Metabolomic Correlates of Pulmonary Arterial Hypertension
por: Alotaibi, Mona, et al.
Publicado: (2023)

Effects of Compound Probiotics on Cecal Microbiota and Metabolome of Swine
por: Li, Jie, et al.
Publicado: (2023)

Reduced nitric oxide bioavailability impairs myocardial oxygen balance during exercise in swine with multiple risk factors
por: van de Wouw, Jens, et al.
Publicado: (2021)

Sex differences in pulmonary vascular control: focus on the nitric oxide pathway
por: de Wijs‐Meijler, Daphne P. M., et al.
Publicado: (2017)

The intracellular proteome of African swine fever virus
por: Keßler, Catharina, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_vk6euvgkp4m1cjfd33l0m3mvga