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Perioperative lidocaine and dexmedetomidine intravenous infusion reduce the serum levels of NETs and biomarkers of tumor metastasis in lung cancer patients: A prospective, single-center, double-blinded, randomized clinical trial

BACKGROUND: Neutrophil extracellular traps (NETs) can enhance the metastasis of non-small cell lung cancer (NSCLC). As biomarkers of tumor metastasis, metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) together with NETs are essential to endothelial-to-mesenchymal transition (EM...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Ren, Baiqing, Cheng, Muqiao, Liu, Chao, Zheng, Huiwen, Zhang, Jingyue, Chen, Wei, Song, Jie, Zhuang, Jingwen, Liu, Tianya, Wang, Rui, Wang, Zhiping
Format: Online Artikel Text
Sprache:English
Veröffentlicht: Frontiers Media S.A. 2023
Schlagworte:
Online Zugang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003334/
https://www.ncbi.nlm.nih.gov/pubmed/36910600
http://dx.doi.org/10.3389/fonc.2023.1101449