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Expression of Non-T Cell Activation Linker (NTAL) in Jurkat Cells Negatively Regulates TCR Signaling: Potential Role in Rheumatoid Arthritis

T lymphocytes are key players in adaptive immune responses through the recognition of peptide antigens through the T Cell Receptor (TCR). After TCR engagement, a signaling cascade is activated, leading to T cell activation, proliferation, and differentiation into effector cells. Delicate control of...

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Detalles Bibliográficos
Autores principales: Narbona-Sánchez, Isaac, Pérez-Linaza, Alba, Serrano-García, Isabel, Vico-Barranco, Inmaculada, Fernández-Aguilar, Luis M., Poveda-Díaz, José L., Sánchez del Pino, María J., Medina-Varo, Fermín, Arbulo-Echevarria, Mikel M., Aguado, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003381/
https://www.ncbi.nlm.nih.gov/pubmed/36902005
http://dx.doi.org/10.3390/ijms24054574