Transcriptomic Analyses of Brains of RBM8A Conditional Knockout Mice at Different Developmental Stages Reveal Conserved Signaling Pathways Contributing to Neurodevelopmental Diseases

RNA-binding motif 8A (RBM8A) is a core component of the exon junction complex (EJC) that binds pre-mRNAs and regulates their splicing, transport, translation, and nonsense-mediated decay (NMD). Dysfunction in the core proteins has been linked to several detriments in brain development and neuropsych...

Descripción completa

Detalles Bibliográficos
Autores principales: McSweeney, Colleen, Chen, Miranda, Dong, Fengping, Sebastian, Aswathy, Reynolds, Derrick James, Mott, Jennifer, Pei, Zifei, Zou, Jizhong, Shi, Yongsheng, Mao, Yingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003467/
https://www.ncbi.nlm.nih.gov/pubmed/36902031
http://dx.doi.org/10.3390/ijms24054600

Ejemplares similares

Ejemplares similares