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The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes

Non-coding RNAs (ncRNAs) are transcribed from the genome and do not encode proteins. In recent years, ncRNAs have attracted increasing attention as critical participants in gene regulation and disease pathogenesis. Different categories of ncRNAs, which mainly include microRNAs (miRNAs), long non-cod...

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Detalles Bibliográficos
Autores principales: Ren, Jiawen, Jin, Heyue, Zhu, Yumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003511/
https://www.ncbi.nlm.nih.gov/pubmed/36902459
http://dx.doi.org/10.3390/ijms24055030
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author Ren, Jiawen
Jin, Heyue
Zhu, Yumin
author_facet Ren, Jiawen
Jin, Heyue
Zhu, Yumin
author_sort Ren, Jiawen
collection PubMed
description Non-coding RNAs (ncRNAs) are transcribed from the genome and do not encode proteins. In recent years, ncRNAs have attracted increasing attention as critical participants in gene regulation and disease pathogenesis. Different categories of ncRNAs, which mainly include microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), are involved in the progression of pregnancy, while abnormal expression of placental ncRNAs impacts the onset and development of adverse pregnancy outcomes (APOs). Therefore, we reviewed the current status of research on placental ncRNAs and APOs to further understand the regulatory mechanisms of placental ncRNAs, which provides a new perspective for treating and preventing related diseases.
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spelling pubmed-100035112023-03-11 The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes Ren, Jiawen Jin, Heyue Zhu, Yumin Int J Mol Sci Review Non-coding RNAs (ncRNAs) are transcribed from the genome and do not encode proteins. In recent years, ncRNAs have attracted increasing attention as critical participants in gene regulation and disease pathogenesis. Different categories of ncRNAs, which mainly include microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), are involved in the progression of pregnancy, while abnormal expression of placental ncRNAs impacts the onset and development of adverse pregnancy outcomes (APOs). Therefore, we reviewed the current status of research on placental ncRNAs and APOs to further understand the regulatory mechanisms of placental ncRNAs, which provides a new perspective for treating and preventing related diseases. MDPI 2023-03-06 /pmc/articles/PMC10003511/ /pubmed/36902459 http://dx.doi.org/10.3390/ijms24055030 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ren, Jiawen
Jin, Heyue
Zhu, Yumin
The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes
title The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes
title_full The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes
title_fullStr The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes
title_full_unstemmed The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes
title_short The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes
title_sort role of placental non-coding rnas in adverse pregnancy outcomes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003511/
https://www.ncbi.nlm.nih.gov/pubmed/36902459
http://dx.doi.org/10.3390/ijms24055030
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