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The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes
Non-coding RNAs (ncRNAs) are transcribed from the genome and do not encode proteins. In recent years, ncRNAs have attracted increasing attention as critical participants in gene regulation and disease pathogenesis. Different categories of ncRNAs, which mainly include microRNAs (miRNAs), long non-cod...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003511/ https://www.ncbi.nlm.nih.gov/pubmed/36902459 http://dx.doi.org/10.3390/ijms24055030 |
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author | Ren, Jiawen Jin, Heyue Zhu, Yumin |
author_facet | Ren, Jiawen Jin, Heyue Zhu, Yumin |
author_sort | Ren, Jiawen |
collection | PubMed |
description | Non-coding RNAs (ncRNAs) are transcribed from the genome and do not encode proteins. In recent years, ncRNAs have attracted increasing attention as critical participants in gene regulation and disease pathogenesis. Different categories of ncRNAs, which mainly include microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), are involved in the progression of pregnancy, while abnormal expression of placental ncRNAs impacts the onset and development of adverse pregnancy outcomes (APOs). Therefore, we reviewed the current status of research on placental ncRNAs and APOs to further understand the regulatory mechanisms of placental ncRNAs, which provides a new perspective for treating and preventing related diseases. |
format | Online Article Text |
id | pubmed-10003511 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100035112023-03-11 The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes Ren, Jiawen Jin, Heyue Zhu, Yumin Int J Mol Sci Review Non-coding RNAs (ncRNAs) are transcribed from the genome and do not encode proteins. In recent years, ncRNAs have attracted increasing attention as critical participants in gene regulation and disease pathogenesis. Different categories of ncRNAs, which mainly include microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), are involved in the progression of pregnancy, while abnormal expression of placental ncRNAs impacts the onset and development of adverse pregnancy outcomes (APOs). Therefore, we reviewed the current status of research on placental ncRNAs and APOs to further understand the regulatory mechanisms of placental ncRNAs, which provides a new perspective for treating and preventing related diseases. MDPI 2023-03-06 /pmc/articles/PMC10003511/ /pubmed/36902459 http://dx.doi.org/10.3390/ijms24055030 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Ren, Jiawen Jin, Heyue Zhu, Yumin The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes |
title | The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes |
title_full | The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes |
title_fullStr | The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes |
title_full_unstemmed | The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes |
title_short | The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes |
title_sort | role of placental non-coding rnas in adverse pregnancy outcomes |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003511/ https://www.ncbi.nlm.nih.gov/pubmed/36902459 http://dx.doi.org/10.3390/ijms24055030 |
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