Lansoprazole Increases Inorganic Pyrophosphate in Patients with Pseudoxanthoma Elasticum: A Double-Blind, Randomized, Placebo-Controlled Crossover Trial

Pseudoxanthoma elasticum (PXE) is characterized by low levels of inorganic pyrophosphate (PPi) and a high activity of tissue-nonspecific alkaline phosphatase (TNAP). Lansoprazole is a partial inhibitor of TNAP. The aim was to investigate whether lansoprazole increases plasma PPi levels in subjects w...

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Detalles Bibliográficos
Autores principales: Murcia Casas, Belén, Carrillo Linares, Juan Luis, Baquero Aranda, Isabel, Rioja Villodres, José, Merino Bohórquez, Vicente, González Jiménez, Andrés, Rico Corral, Miguel Ángel, Bosch, Ricardo, Sánchez Chaparro, Miguel Ángel, García Fernández, María, Valdivielso, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003519/
https://www.ncbi.nlm.nih.gov/pubmed/36902331
http://dx.doi.org/10.3390/ijms24054899

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