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Cyclodextrin-Based Displacement Strategy of Sterigmatocystin from Serum Albumin as a Novel Approach for Acute Poisoning Detoxification

This study demonstrates that sterigmatocystin (STC) interacts non-covalently with various cyclodextrins (CDs), showing the highest binding affinity for sugammadex (a γ-CD derivative) and γ-CD, and an almost order of magnitude lower affinity for β-CD. This difference in affinity was studied using mol...

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Detalles Bibliográficos
Autores principales: Jakšić, Daniela, Šegvić Klarić, Maja, Rimac, Hrvoje, Kerep, Robert, Piantanida, Ivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003537/
https://www.ncbi.nlm.nih.gov/pubmed/36901918
http://dx.doi.org/10.3390/ijms24054485