A Novel System for the Detection of Spontaneous Abortion-Causing Aneuploidy and Its Erroneous Chromosome Origins through the Combination of Low-Pass Copy Number Variation Sequencing and NGS-Based STR Tests

During the period of 2018–2020, we first combined reported low-pass whole genome sequencing and NGS-based STR tests for miscarriage samples analysis. Compared with G-banding karyotyping, the system increased the detection rate of chromosomal abnormalities in miscarriage samples to 56.4% in 500 unexp...

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Detalles Bibliográficos
Autores principales: Lei, Caixia, Liao, Kai, Zhao, Yuwei, Long, Zhoukai, Zhu, Saijuan, Wu, Junping, Xiao, Min, Zhou, Jing, Zhang, Shuo, Li, Lianbin, Zhu, Yijian, Lu, Daru, Yang, Jingmin, Sun, Xiaoxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003649/
https://www.ncbi.nlm.nih.gov/pubmed/36902595
http://dx.doi.org/10.3390/jcm12051809

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