Skeletal Muscle-Derived Exosomal miR-146a-5p Inhibits Adipogenesis by Mediating Muscle-Fat Axis and Targeting GDF5-PPARγ Signaling

Skeletal muscle-fat interaction is essential for maintaining organismal energy homeostasis and managing obesity by secreting cytokines and exosomes, but the role of the latter as a new mediator in inter-tissue communication remains unclear. Recently, we discovered that miR-146a-5p was mainly enriche...

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Detalles Bibliográficos
Autores principales: Qin, Mengran, Xing, Lipeng, Wu, Jiahan, Wen, Shulei, Luo, Junyi, Chen, Ting, Fan, Yaotian, Zhu, Jiahao, Yang, Lekai, Liu, Jie, Xiong, Jiali, Chen, Xingping, Zhu, Canjun, Wang, Songbo, Wang, Lina, Shu, Gang, Jiang, Qingyan, Zhang, Yongliang, Sun, Jiajie, Xi, Qianyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003660/
https://www.ncbi.nlm.nih.gov/pubmed/36901991
http://dx.doi.org/10.3390/ijms24054561

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