Cargando…
Peptides Derived from a Plant Protease Inhibitor of the Coagulation Contact System Decrease Arterial Thrombus Formation in a Murine Model, without Impairing Hemostatic Parameters
Several plant protein inhibitors with anticoagulant properties have been studied and characterized, including the Delonix regia trypsin inhibitor (DrTI). This protein inhibits serine proteases (trypsin) and enzymes directly involved in coagulation, such as plasma kallikrein, factor XIIa, and factor...
Autores principales: | De Souza, Daniel Alexandre, Salu, Bruno Ramos, Nogueira, Ruben Siedlarczyk, de Carvalho Neto, José Carlos Sá, Maffei, Francisco Humberto de Abreu, Oliva, Maria Luiza Vilela |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003694/ https://www.ncbi.nlm.nih.gov/pubmed/36902597 http://dx.doi.org/10.3390/jcm12051810 |
Ejemplares similares
-
A snake venom-analog peptide that inhibits SARS-CoV-2 and papain-like protease displays antithrombotic activity in mice arterial thrombosis model, without interfering with bleeding time
por: Nogueira, Ruben Siedlarczyk, et al.
Publicado: (2023) -
The recombinant plant Bauhinia bauhinioides elastase inhibitor reduces rat thrombus without alterations in hemostatic parameters
por: Oliveira, Cleide, et al.
Publicado: (2021) -
Proliferation and Invasion of Melanoma Are Suppressed by a Plant Protease Inhibitor, Leading to Downregulation of Survival/Death-Related Proteins
por: Bonturi, Camila Ramalho, et al.
Publicado: (2022) -
The EHA Research Roadmap: Blood Coagulation and Hemostatic Disorders
por: Eichinger, Sabine, et al.
Publicado: (2021) -
Hemostatic Evaluation With Viscoelastic Coagulation Monitor: A Nicu Experience
por: Amelio, Giacomo Simeone, et al.
Publicado: (2022)