Acral Melanoma Is Infiltrated with cDC1s and Functional Exhausted CD8 T Cells Similar to the Cutaneous Melanoma of Sun-Exposed Skin

Acral melanoma (AM) is the most common melanoma in non-Caucasian populations, yet it remains largely understudied. As AM lacks the UV-radiation mutational signatures that characterize other cutaneous melanomas, it is considered devoid of immunogenicity and is rarely included in clinical trials asses...

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Detalles Bibliográficos
Autores principales: De Leon-Rodríguez, Saraí G., Aguilar-Flores, Cristina, Gajón, Julián A., Mantilla, Alejandra, Gerson-Cwilich, Raquel, Martínez-Herrera, José Fabián, Rodríguez-Soto, Benigno E., Gutiérrez-Quiroz, Claudia T., Pérez-Koldenkova, Vadim, Muñoz-Cruz, Samira, Bonifaz, Laura C., Fuentes-Pananá, Ezequiel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003718/
https://www.ncbi.nlm.nih.gov/pubmed/36902214
http://dx.doi.org/10.3390/ijms24054786

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