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Increasing Number of Cases Due to Candida auris in North Italy, July 2019–December 2022

Candida auris is an emerging fungus that represents a serious health threat globally. In Italy, the first case was detected in July 2019. Then, one case was reported to the Ministry of Health (MoH) on January 2020. Nine months later, a huge number of cases were reported in northern Italy. Overall, 3...

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Autores principales: Sticchi, Camilla, Raso, Roberto, Ferrara, Lorenza, Vecchi, Elena, Ferrero, Loredana, Filippi, Daniela, Finotto, Giuseppe, Frassinelli, Elena, Silvestre, Carlo, Zozzoli, Susanna, Ambretti, Simone, Diegoli, Giuseppe, Gagliotti, Carlo, Moro, Maria Luisa, Ricchizzi, Enrico, Tumietto, Fabio, Russo, Francesca, Tonon, Michele, Maraglino, Francesco, Rezza, Giovanni, Sabbatucci, Michela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003924/
https://www.ncbi.nlm.nih.gov/pubmed/36902700
http://dx.doi.org/10.3390/jcm12051912
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author Sticchi, Camilla
Raso, Roberto
Ferrara, Lorenza
Vecchi, Elena
Ferrero, Loredana
Filippi, Daniela
Finotto, Giuseppe
Frassinelli, Elena
Silvestre, Carlo
Zozzoli, Susanna
Ambretti, Simone
Diegoli, Giuseppe
Gagliotti, Carlo
Moro, Maria Luisa
Ricchizzi, Enrico
Tumietto, Fabio
Russo, Francesca
Tonon, Michele
Maraglino, Francesco
Rezza, Giovanni
Sabbatucci, Michela
author_facet Sticchi, Camilla
Raso, Roberto
Ferrara, Lorenza
Vecchi, Elena
Ferrero, Loredana
Filippi, Daniela
Finotto, Giuseppe
Frassinelli, Elena
Silvestre, Carlo
Zozzoli, Susanna
Ambretti, Simone
Diegoli, Giuseppe
Gagliotti, Carlo
Moro, Maria Luisa
Ricchizzi, Enrico
Tumietto, Fabio
Russo, Francesca
Tonon, Michele
Maraglino, Francesco
Rezza, Giovanni
Sabbatucci, Michela
author_sort Sticchi, Camilla
collection PubMed
description Candida auris is an emerging fungus that represents a serious health threat globally. In Italy, the first case was detected in July 2019. Then, one case was reported to the Ministry of Health (MoH) on January 2020. Nine months later, a huge number of cases were reported in northern Italy. Overall, 361 cases were detected in 17 healthcare facilities between July 2019 and December 2022 in the Liguria, Piedmont, Emilia-Romagna, and Veneto regions, including 146 (40.4%) deaths. The majority of cases (91.8%) were considered as colonised. Only one had a history of travel abroad. Microbiological data on seven isolates showed that all but one strain (85.7%) were resistant to fluconazole. All the environmental samples tested negative. Weekly screening of contacts was performed by the healthcare facilities. Infection prevention and control (IPC) measures were applied locally. The MoH nominated a National Reference Laboratory to characterise C. auris isolates and store the strains. In 2021, Italy posted two messages through the Epidemic Intelligence Information System (EPIS) to inform on the cases. On February 2022, a rapid risk assessment indicated a high risk for further spread within Italy, but a low risk of spread to other countries.
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spelling pubmed-100039242023-03-11 Increasing Number of Cases Due to Candida auris in North Italy, July 2019–December 2022 Sticchi, Camilla Raso, Roberto Ferrara, Lorenza Vecchi, Elena Ferrero, Loredana Filippi, Daniela Finotto, Giuseppe Frassinelli, Elena Silvestre, Carlo Zozzoli, Susanna Ambretti, Simone Diegoli, Giuseppe Gagliotti, Carlo Moro, Maria Luisa Ricchizzi, Enrico Tumietto, Fabio Russo, Francesca Tonon, Michele Maraglino, Francesco Rezza, Giovanni Sabbatucci, Michela J Clin Med Article Candida auris is an emerging fungus that represents a serious health threat globally. In Italy, the first case was detected in July 2019. Then, one case was reported to the Ministry of Health (MoH) on January 2020. Nine months later, a huge number of cases were reported in northern Italy. Overall, 361 cases were detected in 17 healthcare facilities between July 2019 and December 2022 in the Liguria, Piedmont, Emilia-Romagna, and Veneto regions, including 146 (40.4%) deaths. The majority of cases (91.8%) were considered as colonised. Only one had a history of travel abroad. Microbiological data on seven isolates showed that all but one strain (85.7%) were resistant to fluconazole. All the environmental samples tested negative. Weekly screening of contacts was performed by the healthcare facilities. Infection prevention and control (IPC) measures were applied locally. The MoH nominated a National Reference Laboratory to characterise C. auris isolates and store the strains. In 2021, Italy posted two messages through the Epidemic Intelligence Information System (EPIS) to inform on the cases. On February 2022, a rapid risk assessment indicated a high risk for further spread within Italy, but a low risk of spread to other countries. MDPI 2023-02-28 /pmc/articles/PMC10003924/ /pubmed/36902700 http://dx.doi.org/10.3390/jcm12051912 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sticchi, Camilla
Raso, Roberto
Ferrara, Lorenza
Vecchi, Elena
Ferrero, Loredana
Filippi, Daniela
Finotto, Giuseppe
Frassinelli, Elena
Silvestre, Carlo
Zozzoli, Susanna
Ambretti, Simone
Diegoli, Giuseppe
Gagliotti, Carlo
Moro, Maria Luisa
Ricchizzi, Enrico
Tumietto, Fabio
Russo, Francesca
Tonon, Michele
Maraglino, Francesco
Rezza, Giovanni
Sabbatucci, Michela
Increasing Number of Cases Due to Candida auris in North Italy, July 2019–December 2022
title Increasing Number of Cases Due to Candida auris in North Italy, July 2019–December 2022
title_full Increasing Number of Cases Due to Candida auris in North Italy, July 2019–December 2022
title_fullStr Increasing Number of Cases Due to Candida auris in North Italy, July 2019–December 2022
title_full_unstemmed Increasing Number of Cases Due to Candida auris in North Italy, July 2019–December 2022
title_short Increasing Number of Cases Due to Candida auris in North Italy, July 2019–December 2022
title_sort increasing number of cases due to candida auris in north italy, july 2019–december 2022
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003924/
https://www.ncbi.nlm.nih.gov/pubmed/36902700
http://dx.doi.org/10.3390/jcm12051912
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