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Effect of Bioactive Filler Addition on the Mechanical and Biological Properties of Resin-Modified Glass Ionomer
The maintenance of affected dentin can promote the greater conservation of tooth structure. The development of materials that have properties capable of reducing the demineralizing potential and/or even helping in dental remineralization is important for conservative dentistry. This study aimed to e...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004000/ https://www.ncbi.nlm.nih.gov/pubmed/36902881 http://dx.doi.org/10.3390/ma16051765 |
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author | Diniz, Ana Carolina Bauer, José Veloso, Suzanni do Amaral Rodrigues Abreu-Pereira, César Augusto Carvalho, Ceci Nunes Leitão, Tarcísio Jorge Firoozmand, Leily Macedo Maia-Filho, Etevaldo Matos |
author_facet | Diniz, Ana Carolina Bauer, José Veloso, Suzanni do Amaral Rodrigues Abreu-Pereira, César Augusto Carvalho, Ceci Nunes Leitão, Tarcísio Jorge Firoozmand, Leily Macedo Maia-Filho, Etevaldo Matos |
author_sort | Diniz, Ana Carolina |
collection | PubMed |
description | The maintenance of affected dentin can promote the greater conservation of tooth structure. The development of materials that have properties capable of reducing the demineralizing potential and/or even helping in dental remineralization is important for conservative dentistry. This study aimed to evaluate, in vitro, the alkalizing potential, fluoride as well as calcium ion release ability, antimicrobial activity, and dentin remineralization properties of resin-modified glass ionomer cement (RMGIC) incorporated with a bioactive filler (niobium phosphate (NbG) and bioglass (45S5)). The study samples were grouped into RMGIC, NbG, and 45S5. The materials’ alkalizing potential, ability to release calcium as well as fluoride ions, and antimicrobial properties concerning Streptococcus mutans UA159 biofilms were analyzed. The remineralization potential was evaluated using the Knoop microhardness test, which was performed at different depths. The alkalizing and fluoride release potential was higher for the 45S5 group (p < 0.001) over time. An increase in the microhardness of demineralized dentin was observed in the 45S5 and NbG groups (p < 0.001). No differences in biofilm formation were observed between the bioactive materials, although 45S5 exhibited lower biofilm acidogenicity at different time points (p < 0.001) and greater calcium ion release in the microbial environment. A resin-modified glass ionomer cement enriched with bioactive glasses, particularly 45S5, is a promising alternative for the treatment of demineralized dentin. |
format | Online Article Text |
id | pubmed-10004000 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100040002023-03-11 Effect of Bioactive Filler Addition on the Mechanical and Biological Properties of Resin-Modified Glass Ionomer Diniz, Ana Carolina Bauer, José Veloso, Suzanni do Amaral Rodrigues Abreu-Pereira, César Augusto Carvalho, Ceci Nunes Leitão, Tarcísio Jorge Firoozmand, Leily Macedo Maia-Filho, Etevaldo Matos Materials (Basel) Article The maintenance of affected dentin can promote the greater conservation of tooth structure. The development of materials that have properties capable of reducing the demineralizing potential and/or even helping in dental remineralization is important for conservative dentistry. This study aimed to evaluate, in vitro, the alkalizing potential, fluoride as well as calcium ion release ability, antimicrobial activity, and dentin remineralization properties of resin-modified glass ionomer cement (RMGIC) incorporated with a bioactive filler (niobium phosphate (NbG) and bioglass (45S5)). The study samples were grouped into RMGIC, NbG, and 45S5. The materials’ alkalizing potential, ability to release calcium as well as fluoride ions, and antimicrobial properties concerning Streptococcus mutans UA159 biofilms were analyzed. The remineralization potential was evaluated using the Knoop microhardness test, which was performed at different depths. The alkalizing and fluoride release potential was higher for the 45S5 group (p < 0.001) over time. An increase in the microhardness of demineralized dentin was observed in the 45S5 and NbG groups (p < 0.001). No differences in biofilm formation were observed between the bioactive materials, although 45S5 exhibited lower biofilm acidogenicity at different time points (p < 0.001) and greater calcium ion release in the microbial environment. A resin-modified glass ionomer cement enriched with bioactive glasses, particularly 45S5, is a promising alternative for the treatment of demineralized dentin. MDPI 2023-02-21 /pmc/articles/PMC10004000/ /pubmed/36902881 http://dx.doi.org/10.3390/ma16051765 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Diniz, Ana Carolina Bauer, José Veloso, Suzanni do Amaral Rodrigues Abreu-Pereira, César Augusto Carvalho, Ceci Nunes Leitão, Tarcísio Jorge Firoozmand, Leily Macedo Maia-Filho, Etevaldo Matos Effect of Bioactive Filler Addition on the Mechanical and Biological Properties of Resin-Modified Glass Ionomer |
title | Effect of Bioactive Filler Addition on the Mechanical and Biological Properties of Resin-Modified Glass Ionomer |
title_full | Effect of Bioactive Filler Addition on the Mechanical and Biological Properties of Resin-Modified Glass Ionomer |
title_fullStr | Effect of Bioactive Filler Addition on the Mechanical and Biological Properties of Resin-Modified Glass Ionomer |
title_full_unstemmed | Effect of Bioactive Filler Addition on the Mechanical and Biological Properties of Resin-Modified Glass Ionomer |
title_short | Effect of Bioactive Filler Addition on the Mechanical and Biological Properties of Resin-Modified Glass Ionomer |
title_sort | effect of bioactive filler addition on the mechanical and biological properties of resin-modified glass ionomer |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004000/ https://www.ncbi.nlm.nih.gov/pubmed/36902881 http://dx.doi.org/10.3390/ma16051765 |
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