Cargando…

Effect of Bioactive Filler Addition on the Mechanical and Biological Properties of Resin-Modified Glass Ionomer

The maintenance of affected dentin can promote the greater conservation of tooth structure. The development of materials that have properties capable of reducing the demineralizing potential and/or even helping in dental remineralization is important for conservative dentistry. This study aimed to e...

Descripción completa

Detalles Bibliográficos
Autores principales: Diniz, Ana Carolina, Bauer, José, Veloso, Suzanni do Amaral Rodrigues, Abreu-Pereira, César Augusto, Carvalho, Ceci Nunes, Leitão, Tarcísio Jorge, Firoozmand, Leily Macedo, Maia-Filho, Etevaldo Matos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004000/
https://www.ncbi.nlm.nih.gov/pubmed/36902881
http://dx.doi.org/10.3390/ma16051765
_version_ 1784904735735676928
author Diniz, Ana Carolina
Bauer, José
Veloso, Suzanni do Amaral Rodrigues
Abreu-Pereira, César Augusto
Carvalho, Ceci Nunes
Leitão, Tarcísio Jorge
Firoozmand, Leily Macedo
Maia-Filho, Etevaldo Matos
author_facet Diniz, Ana Carolina
Bauer, José
Veloso, Suzanni do Amaral Rodrigues
Abreu-Pereira, César Augusto
Carvalho, Ceci Nunes
Leitão, Tarcísio Jorge
Firoozmand, Leily Macedo
Maia-Filho, Etevaldo Matos
author_sort Diniz, Ana Carolina
collection PubMed
description The maintenance of affected dentin can promote the greater conservation of tooth structure. The development of materials that have properties capable of reducing the demineralizing potential and/or even helping in dental remineralization is important for conservative dentistry. This study aimed to evaluate, in vitro, the alkalizing potential, fluoride as well as calcium ion release ability, antimicrobial activity, and dentin remineralization properties of resin-modified glass ionomer cement (RMGIC) incorporated with a bioactive filler (niobium phosphate (NbG) and bioglass (45S5)). The study samples were grouped into RMGIC, NbG, and 45S5. The materials’ alkalizing potential, ability to release calcium as well as fluoride ions, and antimicrobial properties concerning Streptococcus mutans UA159 biofilms were analyzed. The remineralization potential was evaluated using the Knoop microhardness test, which was performed at different depths. The alkalizing and fluoride release potential was higher for the 45S5 group (p < 0.001) over time. An increase in the microhardness of demineralized dentin was observed in the 45S5 and NbG groups (p < 0.001). No differences in biofilm formation were observed between the bioactive materials, although 45S5 exhibited lower biofilm acidogenicity at different time points (p < 0.001) and greater calcium ion release in the microbial environment. A resin-modified glass ionomer cement enriched with bioactive glasses, particularly 45S5, is a promising alternative for the treatment of demineralized dentin.
format Online
Article
Text
id pubmed-10004000
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-100040002023-03-11 Effect of Bioactive Filler Addition on the Mechanical and Biological Properties of Resin-Modified Glass Ionomer Diniz, Ana Carolina Bauer, José Veloso, Suzanni do Amaral Rodrigues Abreu-Pereira, César Augusto Carvalho, Ceci Nunes Leitão, Tarcísio Jorge Firoozmand, Leily Macedo Maia-Filho, Etevaldo Matos Materials (Basel) Article The maintenance of affected dentin can promote the greater conservation of tooth structure. The development of materials that have properties capable of reducing the demineralizing potential and/or even helping in dental remineralization is important for conservative dentistry. This study aimed to evaluate, in vitro, the alkalizing potential, fluoride as well as calcium ion release ability, antimicrobial activity, and dentin remineralization properties of resin-modified glass ionomer cement (RMGIC) incorporated with a bioactive filler (niobium phosphate (NbG) and bioglass (45S5)). The study samples were grouped into RMGIC, NbG, and 45S5. The materials’ alkalizing potential, ability to release calcium as well as fluoride ions, and antimicrobial properties concerning Streptococcus mutans UA159 biofilms were analyzed. The remineralization potential was evaluated using the Knoop microhardness test, which was performed at different depths. The alkalizing and fluoride release potential was higher for the 45S5 group (p < 0.001) over time. An increase in the microhardness of demineralized dentin was observed in the 45S5 and NbG groups (p < 0.001). No differences in biofilm formation were observed between the bioactive materials, although 45S5 exhibited lower biofilm acidogenicity at different time points (p < 0.001) and greater calcium ion release in the microbial environment. A resin-modified glass ionomer cement enriched with bioactive glasses, particularly 45S5, is a promising alternative for the treatment of demineralized dentin. MDPI 2023-02-21 /pmc/articles/PMC10004000/ /pubmed/36902881 http://dx.doi.org/10.3390/ma16051765 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Diniz, Ana Carolina
Bauer, José
Veloso, Suzanni do Amaral Rodrigues
Abreu-Pereira, César Augusto
Carvalho, Ceci Nunes
Leitão, Tarcísio Jorge
Firoozmand, Leily Macedo
Maia-Filho, Etevaldo Matos
Effect of Bioactive Filler Addition on the Mechanical and Biological Properties of Resin-Modified Glass Ionomer
title Effect of Bioactive Filler Addition on the Mechanical and Biological Properties of Resin-Modified Glass Ionomer
title_full Effect of Bioactive Filler Addition on the Mechanical and Biological Properties of Resin-Modified Glass Ionomer
title_fullStr Effect of Bioactive Filler Addition on the Mechanical and Biological Properties of Resin-Modified Glass Ionomer
title_full_unstemmed Effect of Bioactive Filler Addition on the Mechanical and Biological Properties of Resin-Modified Glass Ionomer
title_short Effect of Bioactive Filler Addition on the Mechanical and Biological Properties of Resin-Modified Glass Ionomer
title_sort effect of bioactive filler addition on the mechanical and biological properties of resin-modified glass ionomer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004000/
https://www.ncbi.nlm.nih.gov/pubmed/36902881
http://dx.doi.org/10.3390/ma16051765
work_keys_str_mv AT dinizanacarolina effectofbioactivefilleradditiononthemechanicalandbiologicalpropertiesofresinmodifiedglassionomer
AT bauerjose effectofbioactivefilleradditiononthemechanicalandbiologicalpropertiesofresinmodifiedglassionomer
AT velososuzannidoamaralrodrigues effectofbioactivefilleradditiononthemechanicalandbiologicalpropertiesofresinmodifiedglassionomer
AT abreupereiracesaraugusto effectofbioactivefilleradditiononthemechanicalandbiologicalpropertiesofresinmodifiedglassionomer
AT carvalhocecinunes effectofbioactivefilleradditiononthemechanicalandbiologicalpropertiesofresinmodifiedglassionomer
AT leitaotarcisiojorge effectofbioactivefilleradditiononthemechanicalandbiologicalpropertiesofresinmodifiedglassionomer
AT firoozmandleilymacedo effectofbioactivefilleradditiononthemechanicalandbiologicalpropertiesofresinmodifiedglassionomer
AT maiafilhoetevaldomatos effectofbioactivefilleradditiononthemechanicalandbiologicalpropertiesofresinmodifiedglassionomer