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Patent Foramen Ovale and Cryptogenic Stroke: Integrated Management

Patent foramen ovale (PFO) is a common cardiac abnormality with a prevalence of 25% in the general population. PFO has been associated with the paradoxical embolism causing cryptogenic stroke and systemic embolization. Results from clinical trials, meta-analyses, and position papers support percutan...

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Autores principales: Lucà, Fabiana, Pino, Paolo G., Parrini, Iris, Di Fusco, Stefania Angela, Ceravolo, Roberto, Madeo, Andrea, Leone, Angelo, La Mair, Mark, Benedetto, Francesco Antonio, Riccio, Carmine, Oliva, Fabrizio, Colivicchi, Furio, Gulizia, Michele Massimo, Gelsomino, Sandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004032/
https://www.ncbi.nlm.nih.gov/pubmed/36902748
http://dx.doi.org/10.3390/jcm12051952
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author Lucà, Fabiana
Pino, Paolo G.
Parrini, Iris
Di Fusco, Stefania Angela
Ceravolo, Roberto
Madeo, Andrea
Leone, Angelo
La Mair, Mark
Benedetto, Francesco Antonio
Riccio, Carmine
Oliva, Fabrizio
Colivicchi, Furio
Gulizia, Michele Massimo
Gelsomino, Sandro
author_facet Lucà, Fabiana
Pino, Paolo G.
Parrini, Iris
Di Fusco, Stefania Angela
Ceravolo, Roberto
Madeo, Andrea
Leone, Angelo
La Mair, Mark
Benedetto, Francesco Antonio
Riccio, Carmine
Oliva, Fabrizio
Colivicchi, Furio
Gulizia, Michele Massimo
Gelsomino, Sandro
author_sort Lucà, Fabiana
collection PubMed
description Patent foramen ovale (PFO) is a common cardiac abnormality with a prevalence of 25% in the general population. PFO has been associated with the paradoxical embolism causing cryptogenic stroke and systemic embolization. Results from clinical trials, meta-analyses, and position papers support percutaneous PFO device closure (PPFOC), especially if interatrial septal aneurysms coexist and in the presence of large shunts in young patients. Remarkably, accurately evaluating patients to refer to the closure strategy is extremely important. However, the selection of patients for PFO closure is still not so clear. The aim of this review is to update and clarify which patients should be considered for closure treatment.
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spelling pubmed-100040322023-03-11 Patent Foramen Ovale and Cryptogenic Stroke: Integrated Management Lucà, Fabiana Pino, Paolo G. Parrini, Iris Di Fusco, Stefania Angela Ceravolo, Roberto Madeo, Andrea Leone, Angelo La Mair, Mark Benedetto, Francesco Antonio Riccio, Carmine Oliva, Fabrizio Colivicchi, Furio Gulizia, Michele Massimo Gelsomino, Sandro J Clin Med Review Patent foramen ovale (PFO) is a common cardiac abnormality with a prevalence of 25% in the general population. PFO has been associated with the paradoxical embolism causing cryptogenic stroke and systemic embolization. Results from clinical trials, meta-analyses, and position papers support percutaneous PFO device closure (PPFOC), especially if interatrial septal aneurysms coexist and in the presence of large shunts in young patients. Remarkably, accurately evaluating patients to refer to the closure strategy is extremely important. However, the selection of patients for PFO closure is still not so clear. The aim of this review is to update and clarify which patients should be considered for closure treatment. MDPI 2023-03-01 /pmc/articles/PMC10004032/ /pubmed/36902748 http://dx.doi.org/10.3390/jcm12051952 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Lucà, Fabiana
Pino, Paolo G.
Parrini, Iris
Di Fusco, Stefania Angela
Ceravolo, Roberto
Madeo, Andrea
Leone, Angelo
La Mair, Mark
Benedetto, Francesco Antonio
Riccio, Carmine
Oliva, Fabrizio
Colivicchi, Furio
Gulizia, Michele Massimo
Gelsomino, Sandro
Patent Foramen Ovale and Cryptogenic Stroke: Integrated Management
title Patent Foramen Ovale and Cryptogenic Stroke: Integrated Management
title_full Patent Foramen Ovale and Cryptogenic Stroke: Integrated Management
title_fullStr Patent Foramen Ovale and Cryptogenic Stroke: Integrated Management
title_full_unstemmed Patent Foramen Ovale and Cryptogenic Stroke: Integrated Management
title_short Patent Foramen Ovale and Cryptogenic Stroke: Integrated Management
title_sort patent foramen ovale and cryptogenic stroke: integrated management
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004032/
https://www.ncbi.nlm.nih.gov/pubmed/36902748
http://dx.doi.org/10.3390/jcm12051952
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