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Preparation and Surface Characterization of Cerium Dioxide for Separation of (68)Ge/(68)Ga and Other Medicinal Radionuclides

The overall need for the preparation of new medicinal radionuclides has led to the fast development of new sorption materials, extraction agents, and separation methods. Inorganic ion exchangers, mainly hydrous oxides, are the most widely used materials for the separation of medicinal radionuclides....

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Autores principales: Ondrák Fialová, Kateřina, Adámek, Kryštof, Vlk, Martin, Drtinová, Barbora, Štamberg, Karel, Šebesta, Ferdinand, Šlouf, Miroslav, Kozempel, Ján
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004219/
https://www.ncbi.nlm.nih.gov/pubmed/36902874
http://dx.doi.org/10.3390/ma16051758
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author Ondrák Fialová, Kateřina
Adámek, Kryštof
Vlk, Martin
Drtinová, Barbora
Štamberg, Karel
Šebesta, Ferdinand
Šlouf, Miroslav
Kozempel, Ján
author_facet Ondrák Fialová, Kateřina
Adámek, Kryštof
Vlk, Martin
Drtinová, Barbora
Štamberg, Karel
Šebesta, Ferdinand
Šlouf, Miroslav
Kozempel, Ján
author_sort Ondrák Fialová, Kateřina
collection PubMed
description The overall need for the preparation of new medicinal radionuclides has led to the fast development of new sorption materials, extraction agents, and separation methods. Inorganic ion exchangers, mainly hydrous oxides, are the most widely used materials for the separation of medicinal radionuclides. One of the materials that has been studied for a long time is cerium dioxide, a competitive sorption material for the broadly used titanium dioxide. In this study, cerium dioxide was prepared through calcination of ceric nitrate and fully characterized using X-ray powder diffraction (XRPD), infrared spectrometry (FT-IR), scanning and transmission electron microscopy (SEM and TEM), thermogravimetric and differential thermal analysis (TG and DTA), dynamic light scattering (DLS), and analysis of surface area. In order to estimate the sorption mechanism and capacity of the prepared material, characterization of surface functional groups was carried out using acid-base titration and mathematical modeling. Subsequently, the sorption capacity of the prepared material for germanium was measured. It can be stated that the prepared material is prone to exchange anionic species in a wider range of pH than titanium dioxide. This characteristic makes the material superior as a matrix in (68)Ge/(68)Ga radionuclide generators, and its suitability should be further studied in batch, kinetic, and column experiments.
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spelling pubmed-100042192023-03-11 Preparation and Surface Characterization of Cerium Dioxide for Separation of (68)Ge/(68)Ga and Other Medicinal Radionuclides Ondrák Fialová, Kateřina Adámek, Kryštof Vlk, Martin Drtinová, Barbora Štamberg, Karel Šebesta, Ferdinand Šlouf, Miroslav Kozempel, Ján Materials (Basel) Article The overall need for the preparation of new medicinal radionuclides has led to the fast development of new sorption materials, extraction agents, and separation methods. Inorganic ion exchangers, mainly hydrous oxides, are the most widely used materials for the separation of medicinal radionuclides. One of the materials that has been studied for a long time is cerium dioxide, a competitive sorption material for the broadly used titanium dioxide. In this study, cerium dioxide was prepared through calcination of ceric nitrate and fully characterized using X-ray powder diffraction (XRPD), infrared spectrometry (FT-IR), scanning and transmission electron microscopy (SEM and TEM), thermogravimetric and differential thermal analysis (TG and DTA), dynamic light scattering (DLS), and analysis of surface area. In order to estimate the sorption mechanism and capacity of the prepared material, characterization of surface functional groups was carried out using acid-base titration and mathematical modeling. Subsequently, the sorption capacity of the prepared material for germanium was measured. It can be stated that the prepared material is prone to exchange anionic species in a wider range of pH than titanium dioxide. This characteristic makes the material superior as a matrix in (68)Ge/(68)Ga radionuclide generators, and its suitability should be further studied in batch, kinetic, and column experiments. MDPI 2023-02-21 /pmc/articles/PMC10004219/ /pubmed/36902874 http://dx.doi.org/10.3390/ma16051758 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ondrák Fialová, Kateřina
Adámek, Kryštof
Vlk, Martin
Drtinová, Barbora
Štamberg, Karel
Šebesta, Ferdinand
Šlouf, Miroslav
Kozempel, Ján
Preparation and Surface Characterization of Cerium Dioxide for Separation of (68)Ge/(68)Ga and Other Medicinal Radionuclides
title Preparation and Surface Characterization of Cerium Dioxide for Separation of (68)Ge/(68)Ga and Other Medicinal Radionuclides
title_full Preparation and Surface Characterization of Cerium Dioxide for Separation of (68)Ge/(68)Ga and Other Medicinal Radionuclides
title_fullStr Preparation and Surface Characterization of Cerium Dioxide for Separation of (68)Ge/(68)Ga and Other Medicinal Radionuclides
title_full_unstemmed Preparation and Surface Characterization of Cerium Dioxide for Separation of (68)Ge/(68)Ga and Other Medicinal Radionuclides
title_short Preparation and Surface Characterization of Cerium Dioxide for Separation of (68)Ge/(68)Ga and Other Medicinal Radionuclides
title_sort preparation and surface characterization of cerium dioxide for separation of (68)ge/(68)ga and other medicinal radionuclides
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004219/
https://www.ncbi.nlm.nih.gov/pubmed/36902874
http://dx.doi.org/10.3390/ma16051758
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