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Effects of maternal anxiety on fetal and maternal circulation

OBJECTIVE: The aim of this study was to evaluate the association between maternal anxiety in the third trimester and changes in fetal and maternal circulation assessed by Doppler velocimetry. METHODS: This is a prospective, cross-sectional study. The inclusion criteria were good health, a singleton...

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Autores principales: Jorge, Tiago Ferreira, Nomura, Roseli Mieko Yamamoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Médica Brasileira 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004293/
https://www.ncbi.nlm.nih.gov/pubmed/36820770
http://dx.doi.org/10.1590/1806-9282.20221011
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author Jorge, Tiago Ferreira
Nomura, Roseli Mieko Yamamoto
author_facet Jorge, Tiago Ferreira
Nomura, Roseli Mieko Yamamoto
author_sort Jorge, Tiago Ferreira
collection PubMed
description OBJECTIVE: The aim of this study was to evaluate the association between maternal anxiety in the third trimester and changes in fetal and maternal circulation assessed by Doppler velocimetry. METHODS: This is a prospective, cross-sectional study. The inclusion criteria were good health, a singleton pregnancy, maternal age between 18 and 40 years, and gestational age between 34 and 40 weeks. Doppler measurements included mean uterine artery pulsatility index, fetal middle cerebral artery pulsatility index, peak of systolic velocity, umbilical artery, and umbilical vein. The Beck Anxiety Inventory questionnaire, validated for the Brazilian population, with 21 self-reported items, was applied. RESULTS: The study included 34 pregnant women, and 6 (17.7%) presented a total Beck Anxiety Inventory score showing moderate or severe maternal anxiety. The mean maternal age was 28.1 years (SD 5.7 years); the mean gestational age at interview was 36.5 weeks (SD 1.8 weeks), and the mean Beck Anxiety Inventory total score was 12.3 (SD 9.8). The group with moderate or severe anxiety, compared to the group with minimal or mild anxiety, presented an association with lower maternal age (median 21.5 vs. 29.5 years, p=0.019), lower fetal umbilical vein blood flow (median 189.4 vs. 249.5 mL/min, p=0.047), and lower umbilical vein-corrected blood flow (median 68.5 vs. 84.9 mL/kg/min, p=0.038). CONCLUSION: Maternal anxiety may affect fetal circulation patterns in late pregnancy and is associated with reduced blood flow in the fetal umbilical vein. The underlying physiopathology needs further investigation.
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spelling pubmed-100042932023-03-11 Effects of maternal anxiety on fetal and maternal circulation Jorge, Tiago Ferreira Nomura, Roseli Mieko Yamamoto Rev Assoc Med Bras (1992) Original Article OBJECTIVE: The aim of this study was to evaluate the association between maternal anxiety in the third trimester and changes in fetal and maternal circulation assessed by Doppler velocimetry. METHODS: This is a prospective, cross-sectional study. The inclusion criteria were good health, a singleton pregnancy, maternal age between 18 and 40 years, and gestational age between 34 and 40 weeks. Doppler measurements included mean uterine artery pulsatility index, fetal middle cerebral artery pulsatility index, peak of systolic velocity, umbilical artery, and umbilical vein. The Beck Anxiety Inventory questionnaire, validated for the Brazilian population, with 21 self-reported items, was applied. RESULTS: The study included 34 pregnant women, and 6 (17.7%) presented a total Beck Anxiety Inventory score showing moderate or severe maternal anxiety. The mean maternal age was 28.1 years (SD 5.7 years); the mean gestational age at interview was 36.5 weeks (SD 1.8 weeks), and the mean Beck Anxiety Inventory total score was 12.3 (SD 9.8). The group with moderate or severe anxiety, compared to the group with minimal or mild anxiety, presented an association with lower maternal age (median 21.5 vs. 29.5 years, p=0.019), lower fetal umbilical vein blood flow (median 189.4 vs. 249.5 mL/min, p=0.047), and lower umbilical vein-corrected blood flow (median 68.5 vs. 84.9 mL/kg/min, p=0.038). CONCLUSION: Maternal anxiety may affect fetal circulation patterns in late pregnancy and is associated with reduced blood flow in the fetal umbilical vein. The underlying physiopathology needs further investigation. Associação Médica Brasileira 2023-02-20 /pmc/articles/PMC10004293/ /pubmed/36820770 http://dx.doi.org/10.1590/1806-9282.20221011 Text en https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Jorge, Tiago Ferreira
Nomura, Roseli Mieko Yamamoto
Effects of maternal anxiety on fetal and maternal circulation
title Effects of maternal anxiety on fetal and maternal circulation
title_full Effects of maternal anxiety on fetal and maternal circulation
title_fullStr Effects of maternal anxiety on fetal and maternal circulation
title_full_unstemmed Effects of maternal anxiety on fetal and maternal circulation
title_short Effects of maternal anxiety on fetal and maternal circulation
title_sort effects of maternal anxiety on fetal and maternal circulation
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004293/
https://www.ncbi.nlm.nih.gov/pubmed/36820770
http://dx.doi.org/10.1590/1806-9282.20221011
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