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The 2Ih and (OXO)G Proximity Consequences on Charge Transfer through ds-DNA: Theoretical Studies of Clustered DNA Damage

Genetic information is continuously exposed to harmful factors, both intra- and extracellular. Their activity can lead to the formation of different types of DNA damage. Clustered lesions (CDL) are problematic for DNA repair systems. In this study, the short ds-oligos with a CDL containing (R) or (S...

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Detalles Bibliográficos
Autor principal: Karwowski, Boleslaw T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004366/
https://www.ncbi.nlm.nih.gov/pubmed/36903425
http://dx.doi.org/10.3390/molecules28052180