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MWCNTs-TiO(2) Incorporated-Mg Composites to Improve the Mechanical, Corrosion and Biological Characteristics for Use in Biomedical Fields
This study attempts to synthesize MgZn/TiO(2)-MWCNTs composites with varying TiO(2)-MWCNT concentrations using mechanical alloying and a semi-powder metallurgy process coupled with spark plasma sintering. It also aims to investigate the mechanical, corrosion, and antibacterial properties of these co...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004407/ https://www.ncbi.nlm.nih.gov/pubmed/36903033 http://dx.doi.org/10.3390/ma16051919 |
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author | Amirzade-Iranaq, Mohammad Taher Omidi, Mahdi Bakhsheshi-Rad, Hamid Reza Saberi, Abbas Abazari, Somayeh Teymouri, Nadia Naeimi, Farid Sergi, Claudia Ismail, Ahmad Fauzi Sharif, Safian Berto, Filippo |
author_facet | Amirzade-Iranaq, Mohammad Taher Omidi, Mahdi Bakhsheshi-Rad, Hamid Reza Saberi, Abbas Abazari, Somayeh Teymouri, Nadia Naeimi, Farid Sergi, Claudia Ismail, Ahmad Fauzi Sharif, Safian Berto, Filippo |
author_sort | Amirzade-Iranaq, Mohammad Taher |
collection | PubMed |
description | This study attempts to synthesize MgZn/TiO(2)-MWCNTs composites with varying TiO(2)-MWCNT concentrations using mechanical alloying and a semi-powder metallurgy process coupled with spark plasma sintering. It also aims to investigate the mechanical, corrosion, and antibacterial properties of these composites. When compared to the MgZn composite, the microhardness and compressive strength of the MgZn/TiO(2)-MWCNTs composites were enhanced to 79 HV and 269 MPa, respectively. The results of cell culture and viability experiments revealed that incorporating TiO(2)-MWCNTs increased osteoblast proliferation and attachment and enhanced the biocompatibility of the TiO(2)-MWCNTs nanocomposite. It was observed that the corrosion resistance of the Mg-based composite was improved and the corrosion rate was reduced to about 2.1 mm/y with the addition of 10 wt% TiO(2)-1 wt% MWCNTs. In vitro testing for up to 14 days revealed a reduced degradation rate following the incorporation of TiO(2)-MWCNTs reinforcement into a MgZn matrix alloy. Antibacterial evaluations revealed that the composite had antibacterial activity, with an inhibition zone of 3.7 mm against Staphylococcus aureus. The MgZn/TiO(2)-MWCNTs composite structure has great potential for use in orthopedic fracture fixation devices. |
format | Online Article Text |
id | pubmed-10004407 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100044072023-03-11 MWCNTs-TiO(2) Incorporated-Mg Composites to Improve the Mechanical, Corrosion and Biological Characteristics for Use in Biomedical Fields Amirzade-Iranaq, Mohammad Taher Omidi, Mahdi Bakhsheshi-Rad, Hamid Reza Saberi, Abbas Abazari, Somayeh Teymouri, Nadia Naeimi, Farid Sergi, Claudia Ismail, Ahmad Fauzi Sharif, Safian Berto, Filippo Materials (Basel) Article This study attempts to synthesize MgZn/TiO(2)-MWCNTs composites with varying TiO(2)-MWCNT concentrations using mechanical alloying and a semi-powder metallurgy process coupled with spark plasma sintering. It also aims to investigate the mechanical, corrosion, and antibacterial properties of these composites. When compared to the MgZn composite, the microhardness and compressive strength of the MgZn/TiO(2)-MWCNTs composites were enhanced to 79 HV and 269 MPa, respectively. The results of cell culture and viability experiments revealed that incorporating TiO(2)-MWCNTs increased osteoblast proliferation and attachment and enhanced the biocompatibility of the TiO(2)-MWCNTs nanocomposite. It was observed that the corrosion resistance of the Mg-based composite was improved and the corrosion rate was reduced to about 2.1 mm/y with the addition of 10 wt% TiO(2)-1 wt% MWCNTs. In vitro testing for up to 14 days revealed a reduced degradation rate following the incorporation of TiO(2)-MWCNTs reinforcement into a MgZn matrix alloy. Antibacterial evaluations revealed that the composite had antibacterial activity, with an inhibition zone of 3.7 mm against Staphylococcus aureus. The MgZn/TiO(2)-MWCNTs composite structure has great potential for use in orthopedic fracture fixation devices. MDPI 2023-02-25 /pmc/articles/PMC10004407/ /pubmed/36903033 http://dx.doi.org/10.3390/ma16051919 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Amirzade-Iranaq, Mohammad Taher Omidi, Mahdi Bakhsheshi-Rad, Hamid Reza Saberi, Abbas Abazari, Somayeh Teymouri, Nadia Naeimi, Farid Sergi, Claudia Ismail, Ahmad Fauzi Sharif, Safian Berto, Filippo MWCNTs-TiO(2) Incorporated-Mg Composites to Improve the Mechanical, Corrosion and Biological Characteristics for Use in Biomedical Fields |
title | MWCNTs-TiO(2) Incorporated-Mg Composites to Improve the Mechanical, Corrosion and Biological Characteristics for Use in Biomedical Fields |
title_full | MWCNTs-TiO(2) Incorporated-Mg Composites to Improve the Mechanical, Corrosion and Biological Characteristics for Use in Biomedical Fields |
title_fullStr | MWCNTs-TiO(2) Incorporated-Mg Composites to Improve the Mechanical, Corrosion and Biological Characteristics for Use in Biomedical Fields |
title_full_unstemmed | MWCNTs-TiO(2) Incorporated-Mg Composites to Improve the Mechanical, Corrosion and Biological Characteristics for Use in Biomedical Fields |
title_short | MWCNTs-TiO(2) Incorporated-Mg Composites to Improve the Mechanical, Corrosion and Biological Characteristics for Use in Biomedical Fields |
title_sort | mwcnts-tio(2) incorporated-mg composites to improve the mechanical, corrosion and biological characteristics for use in biomedical fields |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004407/ https://www.ncbi.nlm.nih.gov/pubmed/36903033 http://dx.doi.org/10.3390/ma16051919 |
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