Cargando…

Differential effects of NOX2 and NOX4 inhibition after rodent spinal cord injury

Reactive oxygen species (ROS) are a contributing factor to impaired function and pathology after spinal cord injury (SCI). The NADPH oxidase (NOX) enzyme is a key source of ROS; there are several NOX family members, including NOX2 and NOX4, that may play a role in ROS production after SCI. Previousl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khayrullina, Guzal, Bermudez, Sara, Hopkins, Deanna, Yauger, Young, Byrnes, Kimberly R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004500/ https://www.ncbi.nlm.nih.gov/pubmed/36897852 http://dx.doi.org/10.1371/journal.pone.0281045

Ejemplares similares

Inhibition of NOX2 reduces locomotor impairment, inflammation, and oxidative stress after spinal cord injury
por: Khayrullina, Guzal, et al.
Publicado: (2015)

Age exacerbates microglial activation, oxidative stress, inflammatory and NOX2 gene expression, and delays functional recovery in a middle-aged rodent model of spinal cord injury
por: von Leden, Ramona E., et al.
Publicado: (2017)

Cellular and temporal expression of NADPH oxidase (NOX) isotypes after brain injury
por: Cooney, Sean J, et al.
Publicado: (2013)

The effects of insulin on the inflammatory activity of BV2 microglia
por: Brabazon, Fiona, et al.
Publicado: (2018)

Differential contribution of Nox1, Nox2 and Nox4 to kidney vascular oxidative stress and endothelial dysfunction in obesity
por: Muñoz, Mercedes, et al.
Publicado: (2019)

Molecular targeting of NOX4 for neuropathic pain after traumatic injury of the spinal cord
por: Im, Y B, et al.
Publicado: (2012)

Nox
por: Hettche, Thomas, 1964-
Publicado: (1996)

NOX1 and NOX4 are required for the differentiation of mouse F9 cells into extraembryonic endoderm
por: Dickson, Benjamin J., et al.
Publicado: (2017)

The Nox1/Nox4 inhibitor attenuates acute lung injury induced by ischemia-reperfusion in mice
por: Cui, Yu, et al.
Publicado: (2018)

CRISPR/Cas9-mediated knockout of p22phox leads to loss of Nox1 and Nox4, but not Nox5 activity
por: Prior, Kim-Kristin, et al.
Publicado: (2016)

Reactive Oxygen Species Derived from NOX3 and NOX5 Drive Differentiation of Human Oligodendrocytes
por: Accetta, Roberta, et al.
Publicado: (2016)

NOX4–TIM23 interaction regulates NOX4 mitochondrial import and metabolic reprogramming
por: Pandey, Jyotsana, et al.
Publicado: (2023)

NOX4 inhibition promotes the remodeling of dystrophic muscle
por: Hammers, David W.
Publicado: (2022)

NOX, NOX Who is There? The Contribution of NADPH Oxidase One to Beta Cell Dysfunction
por: Taylor-Fishwick, David A.
Publicado: (2013)

Deficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice through Inhibition of Hepatic Stellate Cell Activation
por: Lan, Tian, et al.
Publicado: (2015)

Statins attenuate cholesterol-induced ROS via inhibiting NOX2/NOX4 and mitochondrial pathway in collecting ducts of the kidney
por: Wang, Ani, et al.
Publicado: (2022)

Nox4 promotes endothelial differentiation through chromatin remodeling
por: Hahner, F., et al.
Publicado: (2022)

The role of Nox1 and Nox2 in GPVI-dependent platelet activation and thrombus formation()
por: Walsh, T.G., et al.
Publicado: (2014)

Nox2 and Nox4 mediate tumour necrosis factor-α-induced ventricular remodelling in mice
por: Moe, K T, et al.
Publicado: (2011)

Nox4 – RyR1 – Nox2: Regulators of micro-domain signaling in skeletal muscle
por: Cully, Tanya R., et al.
Publicado: (2020)

Protective effects of valsartan administration on doxorubicin-induced myocardial injury in rats and the role of oxidative stress and NOX2/NOX4 signaling
por: Cheng, Dong, et al.
Publicado: (2020)

Setanaxib (GKT137831) Ameliorates Doxorubicin-Induced Cardiotoxicity by Inhibiting the NOX1/NOX4/Reactive Oxygen Species/MAPK Pathway
por: Zheng, Hui, et al.
Publicado: (2022)

NOX2ko Mice Show Largely Increased Expression of a Mutated NOX2 mRNA Encoding an Inactive NOX2 Protein
por: Göllner, Monika, et al.
Publicado: (2020)

NOX enzymes as drug targets
por: Krause, Karl-Heinz, et al.
Publicado: (2012)

NOX2 and NOX5 are increased in cardiac microvascular endothelium of deceased COVID-19 patients
por: Jiang, Zhu, et al.
Publicado: (2023)

Homocysteine-Induced Apoptosis in Endothelial Cells Coincides With Nuclear NOX2 and Peri-nuclear NOX4 Activity
por: Sipkens, Jessica A., et al.
Publicado: (2011)

Calpain Regulates Reactive Oxygen Species Production during Capacitation through the Activation of NOX2 and NOX4
por: Ortiz-García, César I., et al.
Publicado: (2023)

The NADPH Oxidase Nox4 and Aging in the Heart
por: Ago, Tetsuro, et al.
Publicado: (2010)

Regulation of Monocyte Adhesion and Migration by Nox4
por: Lee, Chi Fung, et al.
Publicado: (2013)

The Role of NOX4 in Parkinson’s Disease with Dementia
por: Choi, Dong-Hee, et al.
Publicado: (2019)

AKF-PD alleviates diabetic nephropathy via blocking the RAGE/AGEs/NOX and PKC/NOX Pathways
por: Qin, Jiao, et al.
Publicado: (2019)

Oxymatrine Ameliorates Memory Impairment in Diabetic Rats by Regulating Oxidative Stress and Apoptosis: Involvement of NOX2/NOX4
por: Huang, Yongpan, et al.
Publicado: (2020)

Antioxidants and NOX1/NOX4 inhibition blocks TGFβ1-induced CCN2 and α-SMA expression in dermal and gingival fibroblasts
por: Murphy-Marshman, Hannah, et al.
Publicado: (2017)

Grape Seed Proanthocyanidin Ameliorates Cardiac Toxicity Induced by Boldenone Undecylenate through Inhibition of NADPH Oxidase and Reduction in the Expression of NOX2 and NOX4
por: Tousson, Ehab, et al.
Publicado: (2018)

Inhibition of NADPH Oxidase 4 (NOX4) Signaling Attenuates Tuberculous Pleural Fibrosis
por: Kim, Youngmi, et al.
Publicado: (2019)

NOX enzymes: potential target for the treatment of acute lung injury
por: Carnesecchi, Stéphanie, et al.
Publicado: (2012)

NOX2 Expression Is Increased in Keratinocytes After Burn Injury
por: Korkmaz, H Ibrahim, et al.
Publicado: (2020)

Effect of NOx on the somatic chromosomes of goldsmiths.
por: Yadav, J S, et al.
Publicado: (1998)

Procalcitonin, cytokine and NOx in diabetic ketoacidosis
por: Suwarto, S, et al.
Publicado: (2008)

The role of NOX inhibitors in neurodegenerative diseases
por: Barua, Sumit, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_j3cn9q9jvcppvj8usao7ee8s0m