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Association between Serum Vitamin D and Metabolic Syndrome in a Sample of Adults in Lebanon

The evidence on the association between vitamin D and metabolic syndrome (MetS) is inconclusive. This was a cross-sectional study to explore the relationship between vitamin D serum levels and MetS in a sample of Lebanese adults (n = 230), free of diseases that affect vitamin D metabolism, recruited...

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Autores principales: Abboud, Myriam, Rizk, Rana, Haidar, Suzan, Mahboub, Nadine, Papandreou, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004784/
https://www.ncbi.nlm.nih.gov/pubmed/36904128
http://dx.doi.org/10.3390/nu15051129
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author Abboud, Myriam
Rizk, Rana
Haidar, Suzan
Mahboub, Nadine
Papandreou, Dimitrios
author_facet Abboud, Myriam
Rizk, Rana
Haidar, Suzan
Mahboub, Nadine
Papandreou, Dimitrios
author_sort Abboud, Myriam
collection PubMed
description The evidence on the association between vitamin D and metabolic syndrome (MetS) is inconclusive. This was a cross-sectional study to explore the relationship between vitamin D serum levels and MetS in a sample of Lebanese adults (n = 230), free of diseases that affect vitamin D metabolism, recruited from an urban large university and neighboring community. MetS was diagnosed according to the International Diabetes Federation criteria. A logistic regression analysis was performed taking MetS as the dependent variable, and vitamin D was forced into the model as an independent variable. The covariates included sociodemographic, dietary, and lifestyle variables. The mean (SD) serum vitamin D was 17.53 (12.40) ng/mL, and the prevalence of MetS was 44.3%. Serum vitamin D was not associated with MetS (OR = 0.99 (95% CI: 0.96, 1.02), p < 0.757), whereas the male sex, compared with the female sex and older age, was associated with higher odds of having MetS (OR = 5.92 (95% CI: 2.44, 14.33), p < 0.001 and OR = 1.08 (95% CI: 1.04, 1.11), p < 0.001, respectively). This result adds to the controversy in this field. Future interventional studies are warranted to better understand the relationship between vitamin D and MetS and metabolic abnormalities.
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spelling pubmed-100047842023-03-11 Association between Serum Vitamin D and Metabolic Syndrome in a Sample of Adults in Lebanon Abboud, Myriam Rizk, Rana Haidar, Suzan Mahboub, Nadine Papandreou, Dimitrios Nutrients Article The evidence on the association between vitamin D and metabolic syndrome (MetS) is inconclusive. This was a cross-sectional study to explore the relationship between vitamin D serum levels and MetS in a sample of Lebanese adults (n = 230), free of diseases that affect vitamin D metabolism, recruited from an urban large university and neighboring community. MetS was diagnosed according to the International Diabetes Federation criteria. A logistic regression analysis was performed taking MetS as the dependent variable, and vitamin D was forced into the model as an independent variable. The covariates included sociodemographic, dietary, and lifestyle variables. The mean (SD) serum vitamin D was 17.53 (12.40) ng/mL, and the prevalence of MetS was 44.3%. Serum vitamin D was not associated with MetS (OR = 0.99 (95% CI: 0.96, 1.02), p < 0.757), whereas the male sex, compared with the female sex and older age, was associated with higher odds of having MetS (OR = 5.92 (95% CI: 2.44, 14.33), p < 0.001 and OR = 1.08 (95% CI: 1.04, 1.11), p < 0.001, respectively). This result adds to the controversy in this field. Future interventional studies are warranted to better understand the relationship between vitamin D and MetS and metabolic abnormalities. MDPI 2023-02-23 /pmc/articles/PMC10004784/ /pubmed/36904128 http://dx.doi.org/10.3390/nu15051129 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Abboud, Myriam
Rizk, Rana
Haidar, Suzan
Mahboub, Nadine
Papandreou, Dimitrios
Association between Serum Vitamin D and Metabolic Syndrome in a Sample of Adults in Lebanon
title Association between Serum Vitamin D and Metabolic Syndrome in a Sample of Adults in Lebanon
title_full Association between Serum Vitamin D and Metabolic Syndrome in a Sample of Adults in Lebanon
title_fullStr Association between Serum Vitamin D and Metabolic Syndrome in a Sample of Adults in Lebanon
title_full_unstemmed Association between Serum Vitamin D and Metabolic Syndrome in a Sample of Adults in Lebanon
title_short Association between Serum Vitamin D and Metabolic Syndrome in a Sample of Adults in Lebanon
title_sort association between serum vitamin d and metabolic syndrome in a sample of adults in lebanon
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004784/
https://www.ncbi.nlm.nih.gov/pubmed/36904128
http://dx.doi.org/10.3390/nu15051129
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