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Twelve-Month Outcomes in Patients with Obesity Following Bariatric Surgery—A Single Centre Experience

Background: As obesity rates continue to rise worldwide, many surgeons consider bariatric procedures as a possible cure for the upcoming obesity pandemic. Excess weight represents a risk factor for multiple metabolic disorders, especially for type 2 diabetes mellitus (T2DM). There is a strong correl...

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Autores principales: Soroceanu, Radu Petru, Timofte, Daniel Vasile, Maxim, Madalina, Platon, Razvan Liviu, Vlasceanu, Vlad, Ciuntu, Bogdan Mihnea, Pinzariu, Alin Constantin, Clim, Andreea, Soroceanu, Andreea, Silistraru, Ioana, Azoicai, Doina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005116/
https://www.ncbi.nlm.nih.gov/pubmed/36904134
http://dx.doi.org/10.3390/nu15051134
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author Soroceanu, Radu Petru
Timofte, Daniel Vasile
Maxim, Madalina
Platon, Razvan Liviu
Vlasceanu, Vlad
Ciuntu, Bogdan Mihnea
Pinzariu, Alin Constantin
Clim, Andreea
Soroceanu, Andreea
Silistraru, Ioana
Azoicai, Doina
author_facet Soroceanu, Radu Petru
Timofte, Daniel Vasile
Maxim, Madalina
Platon, Razvan Liviu
Vlasceanu, Vlad
Ciuntu, Bogdan Mihnea
Pinzariu, Alin Constantin
Clim, Andreea
Soroceanu, Andreea
Silistraru, Ioana
Azoicai, Doina
author_sort Soroceanu, Radu Petru
collection PubMed
description Background: As obesity rates continue to rise worldwide, many surgeons consider bariatric procedures as a possible cure for the upcoming obesity pandemic. Excess weight represents a risk factor for multiple metabolic disorders, especially for type 2 diabetes mellitus (T2DM). There is a strong correlation between the two pathologies. The aim of this study is to highlight the safety and short-term results of laparoscopic sleeve gastrectomy (LSG), Roux-en-Y gastric bypass (RYGB, laparoscopic gastric plication (LGP) and intragastric balloon (IGB) as methods used in the treatment of obesity. We followed the remission or amelioration of comorbidities, tracked metabolic parameters, weight loss curves and hoped to outline the profile of the obese patient in Romania. Methods: The target population of this study was represented by patients (n = 488) with severe obesity who qualified for the metabolic surgery criteria. Starting from 2013 to 2019, patients underwent four types of bariatric procedures and were subsequently monitored over the course of 12 months in the 3rd Surgical Clinic at “Sf. Spiridon” Emergency Hospital Iași. Descriptive evaluation indicators, as well as those of analytical evaluation were used as statistical processing methods. Results: A significant decrease in body weight was recorded during monitoring and was more pronounced for patients who underwent LSG and RYGB. T2DM was identified in 24.6% of patients. Partial remission of T2DM was present in 25.3% of cases, and total remission was identified in 61.4% of patients. Mean blood glucose levels, triglycerides, LDL and total cholesterol levels decreased significantly during monitoring. Vitamin D increased significantly regardless of the type of surgery performed, while mean levels of vitamin B12 decreased significantly during monitoring. Post-operative intraperitoneal bleeding occurred in 6 cases (1.22%) and a reintervention for haemostasis was required. Conclusions: All procedures performed were safe and effective methods of weight loss and improved associated comorbidities and metabolic parameters.
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spelling pubmed-100051162023-03-11 Twelve-Month Outcomes in Patients with Obesity Following Bariatric Surgery—A Single Centre Experience Soroceanu, Radu Petru Timofte, Daniel Vasile Maxim, Madalina Platon, Razvan Liviu Vlasceanu, Vlad Ciuntu, Bogdan Mihnea Pinzariu, Alin Constantin Clim, Andreea Soroceanu, Andreea Silistraru, Ioana Azoicai, Doina Nutrients Article Background: As obesity rates continue to rise worldwide, many surgeons consider bariatric procedures as a possible cure for the upcoming obesity pandemic. Excess weight represents a risk factor for multiple metabolic disorders, especially for type 2 diabetes mellitus (T2DM). There is a strong correlation between the two pathologies. The aim of this study is to highlight the safety and short-term results of laparoscopic sleeve gastrectomy (LSG), Roux-en-Y gastric bypass (RYGB, laparoscopic gastric plication (LGP) and intragastric balloon (IGB) as methods used in the treatment of obesity. We followed the remission or amelioration of comorbidities, tracked metabolic parameters, weight loss curves and hoped to outline the profile of the obese patient in Romania. Methods: The target population of this study was represented by patients (n = 488) with severe obesity who qualified for the metabolic surgery criteria. Starting from 2013 to 2019, patients underwent four types of bariatric procedures and were subsequently monitored over the course of 12 months in the 3rd Surgical Clinic at “Sf. Spiridon” Emergency Hospital Iași. Descriptive evaluation indicators, as well as those of analytical evaluation were used as statistical processing methods. Results: A significant decrease in body weight was recorded during monitoring and was more pronounced for patients who underwent LSG and RYGB. T2DM was identified in 24.6% of patients. Partial remission of T2DM was present in 25.3% of cases, and total remission was identified in 61.4% of patients. Mean blood glucose levels, triglycerides, LDL and total cholesterol levels decreased significantly during monitoring. Vitamin D increased significantly regardless of the type of surgery performed, while mean levels of vitamin B12 decreased significantly during monitoring. Post-operative intraperitoneal bleeding occurred in 6 cases (1.22%) and a reintervention for haemostasis was required. Conclusions: All procedures performed were safe and effective methods of weight loss and improved associated comorbidities and metabolic parameters. MDPI 2023-02-23 /pmc/articles/PMC10005116/ /pubmed/36904134 http://dx.doi.org/10.3390/nu15051134 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Soroceanu, Radu Petru
Timofte, Daniel Vasile
Maxim, Madalina
Platon, Razvan Liviu
Vlasceanu, Vlad
Ciuntu, Bogdan Mihnea
Pinzariu, Alin Constantin
Clim, Andreea
Soroceanu, Andreea
Silistraru, Ioana
Azoicai, Doina
Twelve-Month Outcomes in Patients with Obesity Following Bariatric Surgery—A Single Centre Experience
title Twelve-Month Outcomes in Patients with Obesity Following Bariatric Surgery—A Single Centre Experience
title_full Twelve-Month Outcomes in Patients with Obesity Following Bariatric Surgery—A Single Centre Experience
title_fullStr Twelve-Month Outcomes in Patients with Obesity Following Bariatric Surgery—A Single Centre Experience
title_full_unstemmed Twelve-Month Outcomes in Patients with Obesity Following Bariatric Surgery—A Single Centre Experience
title_short Twelve-Month Outcomes in Patients with Obesity Following Bariatric Surgery—A Single Centre Experience
title_sort twelve-month outcomes in patients with obesity following bariatric surgery—a single centre experience
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005116/
https://www.ncbi.nlm.nih.gov/pubmed/36904134
http://dx.doi.org/10.3390/nu15051134
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