Cargando…

Doxorubicin-Loaded Polyelectrolyte Multilayer Capsules Modified with Antitumor DR5-Specific TRAIL Variant for Targeted Drug Delivery to Tumor Cells

Recently, biodegradable polyelectrolyte multilayer capsules (PMC) have been proposed for anticancer drug delivery. In many cases, microencapsulation allows to concentrate the substance locally and prolong its flow to the cells. To reduce systemic toxicity when delivering highly toxic drugs, such as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gileva, Anastasia, Trushina, Daria, Yagolovich, Anne, Gasparian, Marine, Kurbanova, Leyli, Smirnov, Ivan, Burov, Sergey, Markvicheva, Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005140/ https://www.ncbi.nlm.nih.gov/pubmed/36903780 http://dx.doi.org/10.3390/nano13050902

Ejemplares similares

Amphiphilic Poly(N-vinylpyrrolidone) Nanoparticles Conjugated with DR5-Specific Antitumor Cytokine DR5-B for Targeted Delivery to Cancer Cells
por: Yagolovich, Anne, et al.
Publicado: (2021)

Death Receptors DR4 and DR5 Undergo Spontaneous and Ligand-Mediated Endocytosis and Recycling Regardless of the Sensitivity of Cancer Cells to TRAIL
por: Artykov, Artem A., et al.
Publicado: (2021)

Corrigendum: Death Receptors DR4 and DR5 Undergo Spontaneous and Ligand-Mediated Endocytosis and Recycling Regardless of the Sensitivity of Cancer Cells to TRAIL
por: Artykov, Artem A., et al.
Publicado: (2022)

DR5-Selective TRAIL Variant DR5-B Functionalized with Tumor-Penetrating iRGD Peptide for Enhanced Antitumor Activity against Glioblastoma
por: Yagolovich, Anne V., et al.
Publicado: (2022)

Optimized Heterologous Expression and Efficient Purification of a New TRAIL-Based Antitumor Fusion Protein SRH–DR5-B with Dual VEGFR2 and DR5 Receptor Specificity
por: Yagolovich, Anne V., et al.
Publicado: (2022)

Recent Advances in the Development of Nanodelivery Systems Targeting the TRAIL Death Receptor Pathway
por: Yagolovich, Anne V., et al.
Publicado: (2023)

Genetically Modified DR5-Specific TRAIL Variant DR5-B Revealed Dual Antitumor and Protumoral Effect in Colon Cancer Xenografts and an Improved Pharmacokinetic Profile
por: Yagolovich, Anne V., et al.
Publicado: (2020)

Polyelectrolyte Multilayered Capsules as Biomedical Tools
por: Mateos-Maroto, Ana, et al.
Publicado: (2022)

Chemotherapeutic Agents Sensitize Resistant Cancer Cells to the DR5-Specific Variant DR5-B More Efficiently Than to TRAIL by Modulating the Surface Expression of Death and Decoy Receptors
por: Artykov, Artem A., et al.
Publicado: (2020)

Polyelectrolyte Multilayer Capsule (PEMC)-Based Scaffolds for Tissue Engineering
por: Kastania, Georgia, et al.
Publicado: (2020)

Combination of TRAIL with Bortezomib Shifted Apoptotic Signaling from DR4 to DR5 Death Receptor by Selective Internalization and Degradation of DR4
por: Bychkov, Maxim L., et al.
Publicado: (2014)

Cellular Internalization of Beta-Carotene Loaded Polyelectrolyte Multilayer Capsules by Raman Mapping
por: Leopold, Loredana F., et al.
Publicado: (2020)

In Vitro Bioeffects of Polyelectrolyte Multilayer Microcapsules Post-Loaded with Water-Soluble Cationic Photosensitizer
por: Ermakov, Alexey V., et al.
Publicado: (2020)

Multilayer capsules made of weak polyelectrolytes: a review on the preparation, functionalization and applications in drug delivery
por: Sharma, Varsha, et al.
Publicado: (2020)

Patterned Microstructure Fabrication: Polyelectrolyte Complexes vs Polyelectrolyte Multilayers
por: Gai, Meiyu, et al.
Publicado: (2016)

The Effect of Temperature Treatment on the Structure of Polyelectrolyte Multilayers
por: Zerball, Maximilian, et al.
Publicado: (2016)

Organic and Inorganic Dyes in Polyelectrolyte Multilayer Films
por: Ball, Vincent
Publicado: (2012)

Aquaporin-Containing Proteopolymersomes in Polyelectrolyte Multilayer Membranes
por: Reurink, Dennis M., et al.
Publicado: (2020)

Novel Doxorubicin Derivatives: Synthesis and Cytotoxicity Study in 2D and 3D in Vitro Models
por: Akasov, Roman, et al.
Publicado: (2017)

Influence of Polyelectrolyte Multilayer Properties on Bacterial Adhesion Capacity
por: Kovačević, Davor, et al.
Publicado: (2016)

The Potential of Polyelectrolyte Multilayer Films as Drug Delivery Materials
por: Potaś, Joanna, et al.
Publicado: (2022)

New sight at the organization of layers of multilayer polyelectrolyte microcapsules
por: Musin, Egor V., et al.
Publicado: (2021)

Role of Substrate Type in the Process of Polyelectrolyte Multilayer Formation
por: Mesić, Mia, et al.
Publicado: (2022)

Synergistic antitumor effects of circularly permuted TRAIL with doxorubicin in triple-negative breast cancer: Circularly permuted TRAIL with Dox in TNBC
por: Liu, Jia, et al.
Publicado: (2023)

Multilayered Polyelectrolyte Microcapsules: Interaction with the Enzyme Cytochrome C Oxidase
por: Pastorino, Laura, et al.
Publicado: (2014)

Assembly and Immunological Processing of Polyelectrolyte Multilayers Composed of Antigens and Adjuvants
por: Chiu, Yu-Chieh, et al.
Publicado: (2016)

Viscoelastic Properties of Polyelectrolyte Multilayers Swollen with Ionic Liquid Solutions
por: Parveen, Nagma, et al.
Publicado: (2019)

Electrical Field-Assisted Gene Delivery from Polyelectrolyte Multilayers
por: Cheng, Yu-Che, et al.
Publicado: (2020)

Prediction of coating thickness for polyelectrolyte multilayers via machine learning
por: Gribova, Varvara, et al.
Publicado: (2021)

Polyelectrolyte Multilayers: An Overview on Fabrication, Properties, and Biomedical and Environmental Applications
por: Petrila, Larisa-Maria, et al.
Publicado: (2021)

A study of the subdiffusion of small molecules in charged polyelectrolyte multilayers
por: Vardanyan, I., et al.
Publicado: (2021)

Influence of Molecular Weight on the Performance of Polyelectrolyte Multilayer Nanofiltration Membranes
por: Regenspurg, Jurjen A., et al.
Publicado: (2021)

Quaternized Chitosan/Heparin Polyelectrolyte Multilayer Films for Protein Delivery
por: Urbaniak, Tomasz, et al.
Publicado: (2022)

Tailored Polyelectrolyte Multilayer Systems by Variation of Polyelectrolyte Composition and EDC/NHS Cross-Linking: Physicochemical Characterization and In Vitro Evaluation
por: Schirmer, Uwe, et al.
Publicado: (2022)

Interplay of the Assembly Conditions on Drug Transport Mechanisms in Polyelectrolyte Multilayer Films
por: Bataglioli, Rogério A., et al.
Publicado: (2020)

Incorporation of FGF-2 into Pharmaceutical Grade Fucoidan/Chitosan Polyelectrolyte Multilayers
por: Benbow, Natalie L., et al.
Publicado: (2020)

DNA Polyelectrolyte Multilayer Coatings Are Antifouling and Promote Mammalian Cell Adhesion
por: Ouni, Omar Abdelaziz, et al.
Publicado: (2021)

Polyelectrolyte Multilayer Films as a Potential Buccal Platform for Drug Delivery
por: Pilicheva, Bissera, et al.
Publicado: (2022)

Quenching the Macroporous Collapse of Polyelectrolyte Multilayer Films for Repeated Drug Loading
por: Liang, Zi-Xuan, et al.
Publicado: (2022)

Reduced Graphene Oxide/Polyelectrolyte Multilayers for Fast Resistive Humidity Sensing
por: Noh, Woojin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ogl7hmo57s5hc45q5co4njhp1q