High-throughput genetic engineering of nonmodel and undomesticated bacteria via iterative site-specific genome integration

Efficient genome engineering is critical to understand and use microbial functions. Despite recent development of tools such as CRISPR-Cas gene editing, efficient integration of exogenous DNA with well-characterized functions remains limited to model bacteria. Here, we describe serine recombinase–as...

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Detalles Bibliográficos
Autores principales: Elmore, Joshua R., Dexter, Gara N., Baldino, Henri, Huenemann, Jay D., Francis, Ryan, Peabody, George L., Martinez-Baird, Jessica, Riley, Lauren A., Simmons, Tuesday, Coleman-Derr, Devin, Guss, Adam M., Egbert, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005180/
https://www.ncbi.nlm.nih.gov/pubmed/36897939
http://dx.doi.org/10.1126/sciadv.ade1285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005180/
https://www.ncbi.nlm.nih.gov/pubmed/36897939
http://dx.doi.org/10.1126/sciadv.ade1285

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