Cargando…

Triterpene Derivatives as Potential Inhibitors of the RBD Spike Protein from SARS-CoV-2: An In Silico Approach

The appearance of a new coronavirus, SARS-CoV-2, in 2019 kicked off an international public health emergency. Although rapid progress in vaccination has reduced the number of deaths, the development of alternative treatments to overcome the disease is still necessary. It is known that the infection...

Descripción completa

Detalles Bibliográficos
Autores principales:	Avelar, Mayra, Pedraza-González, Laura, Sinicropi, Adalgisa, Flores-Morales, Virginia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005606/ https://www.ncbi.nlm.nih.gov/pubmed/36903578 http://dx.doi.org/10.3390/molecules28052333

Ejemplares similares

In silico Screening of Natural Compounds as Potential Inhibitors of SARS-CoV-2 Main Protease and Spike RBD: Targets for COVID-19
por: Teli, Divya M., et al.
Publicado: (2021)

Identifying epitopes for cluster of differentiation and design of new peptides inhibitors against human SARS-CoV-2 spike RBD by an in-silico approach
por: Akachar, Jihane, et al.
Publicado: (2020)

Screening and Characterization of Shark-Derived VNARs against SARS-CoV-2 Spike RBD Protein
por: Chen, Yu-Lei, et al.
Publicado: (2022)

Synthesis, In Vitro, and In Silico Analysis of the Antioxidative Activity of Dapsone Imine Derivatives †
por: Guzmán-Ávila, Ricardo, et al.
Publicado: (2021)

Geranii Herba as a Potential Inhibitor of SARS-CoV-2 Main 3CL(pro), Spike RBD, and Regulation of Unfolded Protein Response: An In Silico Approach
por: Arokiyaraj, Selvaraj, et al.
Publicado: (2020)

Quinolines-Based SARS-CoV-2 3CLpro and RdRp Inhibitors and Spike-RBD-ACE2 Inhibitor for Drug-Repurposing Against COVID-19: An in silico Analysis
por: Alexpandi, Rajaiah, et al.
Publicado: (2020)

In silico study of some selective phytochemicals against a hypothetical SARS-CoV-2 spike RBD using molecular docking tools
por: Nag, Anish, et al.
Publicado: (2021)

Quantitative in silico analysis of SARS-CoV-2 S-RBD omicron mutant transmissibility
por: Hanai, Toshihiko
Publicado: (2022)

Global conserved RBD fraction of SARS-CoV-2 S-protein with T500S mutation in silico significantly blocks ACE2 and rejects viral spike
por: Banerjee, Amrita, et al.
Publicado: (2022)

In silico identification of RBD subdomain of spike protein from Pro(322)-Thr(581) for applications in vaccine development against SARS-CoV2
por: Pagadala, Nataraj S, et al.
Publicado: (2021)

Multiepitope Proteins for the Differential Detection of IgG Antibodies against RBD of the Spike Protein and Non-RBD Regions of SARS-CoV-2
por: Gomes, Larissa R., et al.
Publicado: (2021)

Expression, purification and characterization of SARS-CoV-2 spike RBD in ExpiCHO cells
por: De March, Matteo, et al.
Publicado: (2022)

Novel human neutralizing mAbs specific for Spike-RBD of SARS-CoV-2
por: Passariello, Margherita, et al.
Publicado: (2021)

SIM imaging resolves endocytosis of SARS-CoV-2 spike RBD in living cells
por: Miao, Lu, et al.
Publicado: (2023)

Bacillus subtilis spores displaying RBD domain of SARS-CoV-2 spike protein
por: Vetráková, A., et al.
Publicado: (2023)

In silico design of refined ferritin-SARS-CoV-2 glyco-RBD nanoparticle vaccine
por: Masoomi Nomandan, Seyedeh Zeinab, et al.
Publicado: (2022)

Bionics design of affinity peptide inhibitors for SARS-CoV-2 RBD to block SARS-CoV-2 RBD-ACE2 interactions
por: Liu, Xiaofeng, et al.
Publicado: (2023)

In silico screening of known small molecules to bind ACE2 specific RBD on Spike glycoprotein of SARS-CoV-2 for repurposing against COVID-19
por: BR, Bharath, et al.
Publicado: (2020)

Jacareubin inhibits TLR4-induced lung inflammatory response caused by the RBD domain of SARS-CoV-2 Spike protein
por: Segura-Villalobos, Deisy, et al.
Publicado: (2022)

Neohesperidin and spike RBD interaction in omicron and its sub-variants: In silico, structural and simulation studies
por: Singh, Jaikee Kumar, et al.
Publicado: (2023)

Identification of potential SARS-CoV-2 entry inhibitors by targeting the interface region between the spike RBD and human ACE2
por: Gurung, Arun Bahadur, et al.
Publicado: (2021)

The Development of Pharmacophore Models for the Search of New Natural Inhibitors of SARS-CoV-2 Spike RBD–ACE2 Binding Interface
por: Semenov, Valentin A., et al.
Publicado: (2022)

Improved production of SARS-CoV-2 spike receptor-binding domain (RBD) for serology assays
por: Mehalko, Jennifer, et al.
Publicado: (2020)

Improved production of SARS-CoV-2 spike receptor-binding domain (RBD) for serology assays
por: Mehalko, Jennifer, et al.
Publicado: (2021)

Comparative structural analyses of selected spike protein-RBD mutations in SARS-CoV-2 lineages
por: Roy, Urmi
Publicado: (2021)

Development of multivalent nanobodies blocking SARS-CoV-2 infection by targeting RBD of spike protein
por: Lu, Qizhong, et al.
Publicado: (2021)

Assessment of mutations on RBD in the Spike protein of SARS-CoV-2 Alpha, Delta and Omicron variants
por: da Costa, Clauber Henrique Souza, et al.
Publicado: (2022)

Improved Expression of SARS-CoV-2 Spike RBD Using the Insect Cell-Baculovirus System
por: Poodts, Joaquín, et al.
Publicado: (2022)

Anti-Entry Activity of Natural Flavonoids against SARS-CoV-2 by Targeting Spike RBD
por: Meng, Jie-Ru, et al.
Publicado: (2023)

Triterpenic Acid Amides as Potential Inhibitors of the SARS-CoV-2 Main Protease
por: Baev, Dmitry S., et al.
Publicado: (2022)

Peptide modelling and screening against human ACE2 and spike glycoprotein RBD of SARS-CoV-2
por: Rathod, Shravan B., et al.
Publicado: (2020)

The polybasic insert, the RBD of the SARS-CoV-2 spike protein, and the feline coronavirus – evolved or yet to evolve
por: Budhraja, Anshul, et al.
Publicado: (2021)

Biomechanical characterization of SARS-CoV-2 spike RBD and human ACE2 protein-protein interaction
por: Cao, Wenpeng, et al.
Publicado: (2021)

A Collection of Designed Peptides to Target SARS-CoV-2 Spike RBD—ACE2 Interaction
por: Fernandez-Fuentes, Narcis, et al.
Publicado: (2021)

Interactions of Spike-RBD of SARS-CoV-2 and Platelet Factor 4: New Insights in the Etiopathogenesis of Thrombosis
por: Passariello, Margherita, et al.
Publicado: (2021)

Identification of Potential Binding Sites of Sialic Acids on the RBD Domain of SARS-CoV-2 Spike Protein
por: Li, Bingqian, et al.
Publicado: (2021)

Differential Interactions Between Human ACE2 and Spike RBD of SARS-CoV-2 Variants of Concern
por: Kim, Seonghan, et al.
Publicado: (2021)

Differential interactions between human ACE2 and spike RBD of SARS-CoV-2 variants of concern
por: Kim, Seonghan, et al.
Publicado: (2022)

Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes
por: Voss, William N., et al.
Publicado: (2021)

VE607 stabilizes SARS-CoV-2 Spike in the “RBD-up” conformation and inhibits viral entry
por: Ding, Shilei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_lkaucs8dj4pt8b8d6v9rsme0e3