Gamma-Muricholic Acid Inhibits Nonalcoholic Steatohepatitis: Abolishment of Steatosis-Dependent Peroxidative Impairment by FXR/SHP/LXRα/FASN Signaling

Nonalcoholic steatohepatitis (NASH) reflects the outcome of steatosis-based peroxidative impairment. Here, the effect and mechanism of γ-muricholic acid (γ-MCA) on NASH were investigated on the basis of its actions in hepatic steatosis, lipid peroxidation, peroxidative injury, hepatocyte apoptosis,...

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Detalles Bibliográficos
Autores principales: Xie, Yang, Shen, Feng, He, Yafang, Guo, Canjie, Yang, Ruixu, Cao, Haixia, Pan, Qin, Fan, Jiangao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005659/
https://www.ncbi.nlm.nih.gov/pubmed/36904254
http://dx.doi.org/10.3390/nu15051255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005659/
https://www.ncbi.nlm.nih.gov/pubmed/36904254
http://dx.doi.org/10.3390/nu15051255

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