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Gamma-Muricholic Acid Inhibits Nonalcoholic Steatohepatitis: Abolishment of Steatosis-Dependent Peroxidative Impairment by FXR/SHP/LXRα/FASN Signaling
Nonalcoholic steatohepatitis (NASH) reflects the outcome of steatosis-based peroxidative impairment. Here, the effect and mechanism of γ-muricholic acid (γ-MCA) on NASH were investigated on the basis of its actions in hepatic steatosis, lipid peroxidation, peroxidative injury, hepatocyte apoptosis,...
Autores principales: | Xie, Yang, Shen, Feng, He, Yafang, Guo, Canjie, Yang, Ruixu, Cao, Haixia, Pan, Qin, Fan, Jiangao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005659/ https://www.ncbi.nlm.nih.gov/pubmed/36904254 http://dx.doi.org/10.3390/nu15051255 |
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