Cargando…

The Chemopreventive Effects of Chlorogenic Acids, Phenolic Compounds in Coffee, against Inflammation, Cancer, and Neurological Diseases

Coffee is one of the most widely consumed beverages, which has several effects on the human body. In particular, current evidence suggests that coffee consumption is associated with a reduced risk of inflammation, various types of cancers, and certain neurodegenerative diseases. Among the various co...

Descripción completa

Detalles Bibliográficos
Autores principales: Murai, Toshiyuki, Matsuda, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005755/
https://www.ncbi.nlm.nih.gov/pubmed/36903626
http://dx.doi.org/10.3390/molecules28052381
_version_ 1784905159464189952
author Murai, Toshiyuki
Matsuda, Satoru
author_facet Murai, Toshiyuki
Matsuda, Satoru
author_sort Murai, Toshiyuki
collection PubMed
description Coffee is one of the most widely consumed beverages, which has several effects on the human body. In particular, current evidence suggests that coffee consumption is associated with a reduced risk of inflammation, various types of cancers, and certain neurodegenerative diseases. Among the various constituents of coffee, phenolic phytochemicals, more specifically chlorogenic acids, are the most abundant, and there have been many attempts to utilize coffee chlorogenic acid for cancer prevention and therapy. Due to its beneficial biological effect on the human body, coffee is regarded as a functional food. In this review article, we summarize the recent advances and knowledge on the association of phytochemicals contained in coffee as nutraceuticals, with a particular focus on phenolic compounds, their intake, and nutritional biomarkers, with the reduction of disease risk, including inflammation, cancer, and neurological diseases.
format Online
Article
Text
id pubmed-10005755
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-100057552023-03-11 The Chemopreventive Effects of Chlorogenic Acids, Phenolic Compounds in Coffee, against Inflammation, Cancer, and Neurological Diseases Murai, Toshiyuki Matsuda, Satoru Molecules Review Coffee is one of the most widely consumed beverages, which has several effects on the human body. In particular, current evidence suggests that coffee consumption is associated with a reduced risk of inflammation, various types of cancers, and certain neurodegenerative diseases. Among the various constituents of coffee, phenolic phytochemicals, more specifically chlorogenic acids, are the most abundant, and there have been many attempts to utilize coffee chlorogenic acid for cancer prevention and therapy. Due to its beneficial biological effect on the human body, coffee is regarded as a functional food. In this review article, we summarize the recent advances and knowledge on the association of phytochemicals contained in coffee as nutraceuticals, with a particular focus on phenolic compounds, their intake, and nutritional biomarkers, with the reduction of disease risk, including inflammation, cancer, and neurological diseases. MDPI 2023-03-04 /pmc/articles/PMC10005755/ /pubmed/36903626 http://dx.doi.org/10.3390/molecules28052381 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Murai, Toshiyuki
Matsuda, Satoru
The Chemopreventive Effects of Chlorogenic Acids, Phenolic Compounds in Coffee, against Inflammation, Cancer, and Neurological Diseases
title The Chemopreventive Effects of Chlorogenic Acids, Phenolic Compounds in Coffee, against Inflammation, Cancer, and Neurological Diseases
title_full The Chemopreventive Effects of Chlorogenic Acids, Phenolic Compounds in Coffee, against Inflammation, Cancer, and Neurological Diseases
title_fullStr The Chemopreventive Effects of Chlorogenic Acids, Phenolic Compounds in Coffee, against Inflammation, Cancer, and Neurological Diseases
title_full_unstemmed The Chemopreventive Effects of Chlorogenic Acids, Phenolic Compounds in Coffee, against Inflammation, Cancer, and Neurological Diseases
title_short The Chemopreventive Effects of Chlorogenic Acids, Phenolic Compounds in Coffee, against Inflammation, Cancer, and Neurological Diseases
title_sort chemopreventive effects of chlorogenic acids, phenolic compounds in coffee, against inflammation, cancer, and neurological diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005755/
https://www.ncbi.nlm.nih.gov/pubmed/36903626
http://dx.doi.org/10.3390/molecules28052381
work_keys_str_mv AT muraitoshiyuki thechemopreventiveeffectsofchlorogenicacidsphenoliccompoundsincoffeeagainstinflammationcancerandneurologicaldiseases
AT matsudasatoru thechemopreventiveeffectsofchlorogenicacidsphenoliccompoundsincoffeeagainstinflammationcancerandneurologicaldiseases
AT muraitoshiyuki chemopreventiveeffectsofchlorogenicacidsphenoliccompoundsincoffeeagainstinflammationcancerandneurologicaldiseases
AT matsudasatoru chemopreventiveeffectsofchlorogenicacidsphenoliccompoundsincoffeeagainstinflammationcancerandneurologicaldiseases