Bone marrow Adipoq-lineage progenitors are a major cellular source of M-CSF that dominates bone marrow macrophage development, osteoclastogenesis, and bone mass

M-CSF is a critical growth factor for myeloid lineage cells, including monocytes, macrophages, and osteoclasts. Tissue-resident macrophages in most organs rely on local M-CSF. However, it is unclear what specific cells in the bone marrow produce M-CSF to maintain myeloid homeostasis. Here, we found...

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Detalles Bibliográficos
Autores principales: Inoue, Kazuki, Qin, Yongli, Xia, Yuhan, Han, Jie, Yuan, Ruoxi, Sun, Jun, Xu, Ren, Jiang, Jean X, Greenblatt, Matthew B, Zhao, Baohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005769/
https://www.ncbi.nlm.nih.gov/pubmed/36779851
http://dx.doi.org/10.7554/eLife.82118

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