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In situ sequence-specific visualization of single methylated cytosine on tissue sections using ICON probe and rolling-circle amplification
Since epigenetic modifications differ from cell to cell, detecting the DNA methylation status of individual cells is requisite. Therefore, it is important to conduct “morphology-based epigenetics research”, in which the sequence-specific DNA methylation status is observed while maintaining tissue ar...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006048/ https://www.ncbi.nlm.nih.gov/pubmed/36418613 http://dx.doi.org/10.1007/s00418-022-02165-2 |