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Efficacy and safety of high-intensity focused ultrasound ablation for rectus abdominis endometriosis: a 7-year follow-up clinical study
BACKGROUND: The aim of this study was to evaluate the efficacy and safety of high-intensity focused ultrasound (HIFU) for the ablation of rectus abdominis endometriosis (RAE) as a noninvasive modality. METHODS: All patients diagnosed with RAE who underwent HIFU ablation were followed up for 7 years....
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006127/ https://www.ncbi.nlm.nih.gov/pubmed/36915358 http://dx.doi.org/10.21037/qims-22-695 |
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author | Yang, Qinghua Zhang, Xiaoying |
author_facet | Yang, Qinghua Zhang, Xiaoying |
author_sort | Yang, Qinghua |
collection | PubMed |
description | BACKGROUND: The aim of this study was to evaluate the efficacy and safety of high-intensity focused ultrasound (HIFU) for the ablation of rectus abdominis endometriosis (RAE) as a noninvasive modality. METHODS: All patients diagnosed with RAE who underwent HIFU ablation were followed up for 7 years. The following demographic characteristics of the patients were collected and analyzed: lesion location, size, and number; HIFU ablation; and recurrence. RESULTS: HIFU ablated 65 lesions in 56 patients with a median age of 36.5±9.19 years and a median lesion volume of 8.2 cm(3). The main symptom was a palpable painful mass (n=61, 93.9%), which protruded from the skin surface in 6 cases (9.23%). Ultrasound was initially scanned in all patients (n=56, 100%), while 6% (n=3) required magnetic resonance imaging (MRI) to distinguish the features and range of the masses. Ablation was completed with a median sonication time of 393 s, a treatment time of 46 min, 150 W of power, and 63,525 J of total energy to treat lesions with a median volume of 5.03 cm(3). There were no severe complications during the 84-month follow-up period, except for 2 patients who experiences hematuria. The pooled recurrence rate of RAE in this cohort was 1.8% (n=1). CONCLUSIONS: As HIFU is effective and safe and retains the integrity of the abdominal wall, it should be the preferred method for the treatment of RAE. |
format | Online Article Text |
id | pubmed-10006127 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | AME Publishing Company |
record_format | MEDLINE/PubMed |
spelling | pubmed-100061272023-03-12 Efficacy and safety of high-intensity focused ultrasound ablation for rectus abdominis endometriosis: a 7-year follow-up clinical study Yang, Qinghua Zhang, Xiaoying Quant Imaging Med Surg Original Article BACKGROUND: The aim of this study was to evaluate the efficacy and safety of high-intensity focused ultrasound (HIFU) for the ablation of rectus abdominis endometriosis (RAE) as a noninvasive modality. METHODS: All patients diagnosed with RAE who underwent HIFU ablation were followed up for 7 years. The following demographic characteristics of the patients were collected and analyzed: lesion location, size, and number; HIFU ablation; and recurrence. RESULTS: HIFU ablated 65 lesions in 56 patients with a median age of 36.5±9.19 years and a median lesion volume of 8.2 cm(3). The main symptom was a palpable painful mass (n=61, 93.9%), which protruded from the skin surface in 6 cases (9.23%). Ultrasound was initially scanned in all patients (n=56, 100%), while 6% (n=3) required magnetic resonance imaging (MRI) to distinguish the features and range of the masses. Ablation was completed with a median sonication time of 393 s, a treatment time of 46 min, 150 W of power, and 63,525 J of total energy to treat lesions with a median volume of 5.03 cm(3). There were no severe complications during the 84-month follow-up period, except for 2 patients who experiences hematuria. The pooled recurrence rate of RAE in this cohort was 1.8% (n=1). CONCLUSIONS: As HIFU is effective and safe and retains the integrity of the abdominal wall, it should be the preferred method for the treatment of RAE. AME Publishing Company 2023-01-29 2023-03-01 /pmc/articles/PMC10006127/ /pubmed/36915358 http://dx.doi.org/10.21037/qims-22-695 Text en 2023 Quantitative Imaging in Medicine and Surgery. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) . |
spellingShingle | Original Article Yang, Qinghua Zhang, Xiaoying Efficacy and safety of high-intensity focused ultrasound ablation for rectus abdominis endometriosis: a 7-year follow-up clinical study |
title | Efficacy and safety of high-intensity focused ultrasound ablation for rectus abdominis endometriosis: a 7-year follow-up clinical study |
title_full | Efficacy and safety of high-intensity focused ultrasound ablation for rectus abdominis endometriosis: a 7-year follow-up clinical study |
title_fullStr | Efficacy and safety of high-intensity focused ultrasound ablation for rectus abdominis endometriosis: a 7-year follow-up clinical study |
title_full_unstemmed | Efficacy and safety of high-intensity focused ultrasound ablation for rectus abdominis endometriosis: a 7-year follow-up clinical study |
title_short | Efficacy and safety of high-intensity focused ultrasound ablation for rectus abdominis endometriosis: a 7-year follow-up clinical study |
title_sort | efficacy and safety of high-intensity focused ultrasound ablation for rectus abdominis endometriosis: a 7-year follow-up clinical study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006127/ https://www.ncbi.nlm.nih.gov/pubmed/36915358 http://dx.doi.org/10.21037/qims-22-695 |
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