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Efficacy and safety of high-intensity focused ultrasound ablation for rectus abdominis endometriosis: a 7-year follow-up clinical study

BACKGROUND: The aim of this study was to evaluate the efficacy and safety of high-intensity focused ultrasound (HIFU) for the ablation of rectus abdominis endometriosis (RAE) as a noninvasive modality. METHODS: All patients diagnosed with RAE who underwent HIFU ablation were followed up for 7 years....

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Autores principales: Yang, Qinghua, Zhang, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006127/
https://www.ncbi.nlm.nih.gov/pubmed/36915358
http://dx.doi.org/10.21037/qims-22-695
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author Yang, Qinghua
Zhang, Xiaoying
author_facet Yang, Qinghua
Zhang, Xiaoying
author_sort Yang, Qinghua
collection PubMed
description BACKGROUND: The aim of this study was to evaluate the efficacy and safety of high-intensity focused ultrasound (HIFU) for the ablation of rectus abdominis endometriosis (RAE) as a noninvasive modality. METHODS: All patients diagnosed with RAE who underwent HIFU ablation were followed up for 7 years. The following demographic characteristics of the patients were collected and analyzed: lesion location, size, and number; HIFU ablation; and recurrence. RESULTS: HIFU ablated 65 lesions in 56 patients with a median age of 36.5±9.19 years and a median lesion volume of 8.2 cm(3). The main symptom was a palpable painful mass (n=61, 93.9%), which protruded from the skin surface in 6 cases (9.23%). Ultrasound was initially scanned in all patients (n=56, 100%), while 6% (n=3) required magnetic resonance imaging (MRI) to distinguish the features and range of the masses. Ablation was completed with a median sonication time of 393 s, a treatment time of 46 min, 150 W of power, and 63,525 J of total energy to treat lesions with a median volume of 5.03 cm(3). There were no severe complications during the 84-month follow-up period, except for 2 patients who experiences hematuria. The pooled recurrence rate of RAE in this cohort was 1.8% (n=1). CONCLUSIONS: As HIFU is effective and safe and retains the integrity of the abdominal wall, it should be the preferred method for the treatment of RAE.
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spelling pubmed-100061272023-03-12 Efficacy and safety of high-intensity focused ultrasound ablation for rectus abdominis endometriosis: a 7-year follow-up clinical study Yang, Qinghua Zhang, Xiaoying Quant Imaging Med Surg Original Article BACKGROUND: The aim of this study was to evaluate the efficacy and safety of high-intensity focused ultrasound (HIFU) for the ablation of rectus abdominis endometriosis (RAE) as a noninvasive modality. METHODS: All patients diagnosed with RAE who underwent HIFU ablation were followed up for 7 years. The following demographic characteristics of the patients were collected and analyzed: lesion location, size, and number; HIFU ablation; and recurrence. RESULTS: HIFU ablated 65 lesions in 56 patients with a median age of 36.5±9.19 years and a median lesion volume of 8.2 cm(3). The main symptom was a palpable painful mass (n=61, 93.9%), which protruded from the skin surface in 6 cases (9.23%). Ultrasound was initially scanned in all patients (n=56, 100%), while 6% (n=3) required magnetic resonance imaging (MRI) to distinguish the features and range of the masses. Ablation was completed with a median sonication time of 393 s, a treatment time of 46 min, 150 W of power, and 63,525 J of total energy to treat lesions with a median volume of 5.03 cm(3). There were no severe complications during the 84-month follow-up period, except for 2 patients who experiences hematuria. The pooled recurrence rate of RAE in this cohort was 1.8% (n=1). CONCLUSIONS: As HIFU is effective and safe and retains the integrity of the abdominal wall, it should be the preferred method for the treatment of RAE. AME Publishing Company 2023-01-29 2023-03-01 /pmc/articles/PMC10006127/ /pubmed/36915358 http://dx.doi.org/10.21037/qims-22-695 Text en 2023 Quantitative Imaging in Medicine and Surgery. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Original Article
Yang, Qinghua
Zhang, Xiaoying
Efficacy and safety of high-intensity focused ultrasound ablation for rectus abdominis endometriosis: a 7-year follow-up clinical study
title Efficacy and safety of high-intensity focused ultrasound ablation for rectus abdominis endometriosis: a 7-year follow-up clinical study
title_full Efficacy and safety of high-intensity focused ultrasound ablation for rectus abdominis endometriosis: a 7-year follow-up clinical study
title_fullStr Efficacy and safety of high-intensity focused ultrasound ablation for rectus abdominis endometriosis: a 7-year follow-up clinical study
title_full_unstemmed Efficacy and safety of high-intensity focused ultrasound ablation for rectus abdominis endometriosis: a 7-year follow-up clinical study
title_short Efficacy and safety of high-intensity focused ultrasound ablation for rectus abdominis endometriosis: a 7-year follow-up clinical study
title_sort efficacy and safety of high-intensity focused ultrasound ablation for rectus abdominis endometriosis: a 7-year follow-up clinical study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006127/
https://www.ncbi.nlm.nih.gov/pubmed/36915358
http://dx.doi.org/10.21037/qims-22-695
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