Domesticated HERV-W env contributes to the activation of the small conductance Ca(2+)-activated K(+) type 2 channels via decreased 5-HT4 receptor in recent-onset schizophrenia

The human endogenous retroviruses type W family envelope (HERV-W env) gene is located on chromosome 7q21-22. Our previous studies show that HERV-W env is elevated in schizophrenia and HERV-W env can increase calcium influx. Additionally, the 5-HTergic system and particularly 5-hydroxytryptamine (5-H...

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Detalles Bibliográficos
Autores principales: Wu, Xiulin, Yan, Qiujin, Liu, Lianzhong, Xue, Xing, Yao, Wei, Li, Xuhang, Li, Wenshi, Ding, Shuang, Xia, Yaru, Zhang, Dongyan, Zhu, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006216/
https://www.ncbi.nlm.nih.gov/pubmed/36007838
http://dx.doi.org/10.1016/j.virs.2022.08.005

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