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Different NIPBL requirements of cohesin-STAG1 and cohesin-STAG2

Cohesin organizes the genome through the formation of chromatin loops. NIPBL activates cohesin’s ATPase and is essential for loop extrusion, but its requirement for cohesin loading is unclear. Here we have examined the effect of reducing NIPBL levels on the behavior of the two cohesin variants carry...

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Detalles Bibliográficos
Autores principales:	Alonso-Gil, Dácil, Cuadrado, Ana, Giménez-Llorente, Daniel, Rodríguez-Corsino, Miriam, Losada, Ana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006224/ https://www.ncbi.nlm.nih.gov/pubmed/36898992 http://dx.doi.org/10.1038/s41467-023-36900-7

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