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Increased cross-presentation by dendritic cells and enhanced anti-tumour therapy using the Arp2/3 inhibitor CK666
BACKGROUND: Dendritic cell (DC) vaccines for cancer therapy offer the possibility to let the patient’s own immune system kill cancer cells. However, DC vaccines have shown less efficacy than expected due to failure to induce cancer cell killing and by activating T regulatory cells. METHODS: We teste...
Autores principales: | Oliveira, Mariana M. S., D’Aulerio, Roberta, Yong, Tracer, He, Minghui, Baptista, Marisa A. P., Nylén, Susanne, Westerberg, Lisa S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006228/ https://www.ncbi.nlm.nih.gov/pubmed/36631633 http://dx.doi.org/10.1038/s41416-022-02135-4 |
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