C–N bond formation by a polyketide synthase

Assembly-line polyketide synthases (PKSs) are molecular factories that produce diverse metabolites with wide-ranging biological activities. PKSs usually work by constructing and modifying the polyketide backbone successively. Here, we present the cryo-EM structure of CalA3, a chain release PKS modul...

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Detalles Bibliográficos
Autores principales: Wang, Jialiang, Wang, Xiaojie, Li, Xixi, Kong, LiangLiang, Du, Zeqian, Li, Dandan, Gou, Lixia, Wu, Hao, Cao, Wei, Wang, Xiaozheng, Lin, Shuangjun, Shi, Ting, Deng, Zixin, Wang, Zhijun, Liang, Jingdan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006239/
https://www.ncbi.nlm.nih.gov/pubmed/36899013
http://dx.doi.org/10.1038/s41467-023-36989-w

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