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Phase-type models for competing risks, with emphasis on identifiability issues
We first review some main results for phase-type distributions, including a discussion of Coxian distributions and their canonical representations. We then consider the extension of phase-type modeling to cover competing risks. This extension involves the consideration of finite state Markov chains...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer US
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006281/ https://www.ncbi.nlm.nih.gov/pubmed/35132532 http://dx.doi.org/10.1007/s10985-022-09547-7 |
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author | Lindqvist, Bo Henry |
author_facet | Lindqvist, Bo Henry |
author_sort | Lindqvist, Bo Henry |
collection | PubMed |
description | We first review some main results for phase-type distributions, including a discussion of Coxian distributions and their canonical representations. We then consider the extension of phase-type modeling to cover competing risks. This extension involves the consideration of finite state Markov chains with more than one absorbing state, letting each absorbing state correspond to a particular risk. The non-uniqueness of Markov chain representations of phase-type distributions is well known. In the paper we study corresponding issues for the competing risks case with the aim of obtaining identifiable parameterizations. Statistical inference for the Coxian competing risks model is briefly discussed and some real data are analyzed for illustration. |
format | Online Article Text |
id | pubmed-10006281 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-100062812023-03-12 Phase-type models for competing risks, with emphasis on identifiability issues Lindqvist, Bo Henry Lifetime Data Anal Article We first review some main results for phase-type distributions, including a discussion of Coxian distributions and their canonical representations. We then consider the extension of phase-type modeling to cover competing risks. This extension involves the consideration of finite state Markov chains with more than one absorbing state, letting each absorbing state correspond to a particular risk. The non-uniqueness of Markov chain representations of phase-type distributions is well known. In the paper we study corresponding issues for the competing risks case with the aim of obtaining identifiable parameterizations. Statistical inference for the Coxian competing risks model is briefly discussed and some real data are analyzed for illustration. Springer US 2022-02-08 2023 /pmc/articles/PMC10006281/ /pubmed/35132532 http://dx.doi.org/10.1007/s10985-022-09547-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Lindqvist, Bo Henry Phase-type models for competing risks, with emphasis on identifiability issues |
title | Phase-type models for competing risks, with emphasis on identifiability issues |
title_full | Phase-type models for competing risks, with emphasis on identifiability issues |
title_fullStr | Phase-type models for competing risks, with emphasis on identifiability issues |
title_full_unstemmed | Phase-type models for competing risks, with emphasis on identifiability issues |
title_short | Phase-type models for competing risks, with emphasis on identifiability issues |
title_sort | phase-type models for competing risks, with emphasis on identifiability issues |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006281/ https://www.ncbi.nlm.nih.gov/pubmed/35132532 http://dx.doi.org/10.1007/s10985-022-09547-7 |
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