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Taurolidine improved protection against highly pathogenetic avian influenza H5N1 virus lethal-infection in mouse model by regulating the NF-κB signaling pathway

Taurolidine (TRD), a derivative of taurine, has anti-bacterial and anti-tumor effects by chemically reacting with cell-walls, endotoxins and exotoxins to inhibit the adhesion of microorganisms. However, its application in antiviral therapy is seldom reported. Here, we reported that TRD significantly...

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Detalles Bibliográficos
Autores principales: Lv, Chaoxiang, Li, Yuanguo, Wang, Tiecheng, Zhang, Qiqi, Qi, Jing, Sima, Mingwei, Li, Entao, Qin, Tian, Shi, Zhuangzhuang, Li, Fangxu, Wang, Xuefeng, Sun, Weiyang, Feng, Na, Yang, Songtao, Xia, Xianzhu, Jin, Ningyi, Zhou, Yifa, Gao, Yuwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006309/
https://www.ncbi.nlm.nih.gov/pubmed/36450323
http://dx.doi.org/10.1016/j.virs.2022.11.010