Cargando…

Short‐term semaglutide treatment improves FGF21 responsiveness in primary hepatocytes isolated from high fat diet challenged mice

Metabolic functions of GLP‐1 and its analogues have been extensively investigated. In addition to acting as an incretin and reducing body weight, we and others have suggested the existence of GLP‐1/fibroblast growth factor 21 (FGF21) axis in which liver mediates certain functions of GLP‐1 receptor a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feng, Jia Nuo, Shao, Weijuan, Jin, Tianru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006666/ https://www.ncbi.nlm.nih.gov/pubmed/36905134 http://dx.doi.org/10.14814/phy2.15620

Ejemplares similares

Hepatic hormone FGF21 and its analogues in clinical trials
por: Shao, Weijuan, et al.
Publicado: (2022)

Head Over Hepatocytes for FGF21
por: Potthoff, Matthew J., et al.
Publicado: (2014)

Nrf2 Represses FGF21 During Long-Term High-Fat Diet–Induced Obesity in Mice
por: Chartoumpekis, Dionysios V., et al.
Publicado: (2011)

Metformin Stimulates FGF21 Expression in Primary Hepatocytes
por: Nygaard, Eva B., et al.
Publicado: (2012)

Effects of semaglutide on vascular structure and proteomics in high-fat diet-induced obese mice
por: Yue, Lin, et al.
Publicado: (2022)

Epigallocatechin-3-gallate ameliorates hepatic damages by relieve FGF21 resistance and promotion of FGF21–AMPK pathway in mice fed a high fat diet
por: Zhang, Yuanyuan, et al.
Publicado: (2022)

Improved FGF21 Sensitivity and Restored FGF21 Signaling Pathway in High-Fat Diet/Streptozotocin-Induced Diabetic Rats After Duodenal-Jejunal Bypass and Sleeve Gastrectomy
por: Liu, Qiaoran, et al.
Publicado: (2019)

Ahnak deficiency attenuates high-fat diet-induced fatty liver in mice through FGF21 induction
por: Kim, Yo Na, et al.
Publicado: (2021)

Phosphorylated proteomics-based analysis of the effects of semaglutide on hippocampi of high-fat diet-induced-obese mice
por: Chen, Xiaoyi, et al.
Publicado: (2023)

Circulating FGF21 in humans is potently induced by short term overfeeding of carbohydrates
por: Lundsgaard, Anne-Marie, et al.
Publicado: (2016)

Curcumin Prevents High Fat Diet Induced Insulin Resistance and Obesity via Attenuating Lipogenesis in Liver and Inflammatory Pathway in Adipocytes
por: Shao, Weijuan, et al.
Publicado: (2012)

Fgf21 Impairs Adipocyte Insulin Sensitivity in Mice Fed a Low-Carbohydrate, High-Fat Ketogenic Diet
por: Murata, Yusuke, et al.
Publicado: (2013)

Fibroblast Growth Factor 21 (FGF21) Protects against High Fat Diet Induced Inflammation and Islet Hyperplasia in Pancreas
por: Singhal, Garima, et al.
Publicado: (2016)

β-Hydroxybutyrate upregulates FGF21 expression through inhibition of histone deacetylases in hepatocytes
por: Yan, Aili, et al.
Publicado: (2022)

Whey protein isolate inhibits hepatic FGF21 production, which precedes weight gain, hyperinsulinemia and hyperglycemia in mice fed a high-fat diet
por: Nonogaki, Katsunori, et al.
Publicado: (2020)

Deficiency of Cathelicidin Attenuates High-Fat Diet Plus Alcohol-Induced Liver Injury through FGF21/Adiponectin Regulation
por: Li, Fengyuan, et al.
Publicado: (2021)

Deficiency of fibroblast growth factor 21 (FGF21) promotes hepatocellular carcinoma (HCC) in mice on a long term obesogenic diet
por: Singhal, Garima, et al.
Publicado: (2018)

CREBH Improves Diet-Induced Obesity, Insulin Resistance, and Metabolic Disturbances by FGF21-Dependent and FGF21-Independent Mechanisms
por: Satoh, Aoi, et al.
Publicado: (2020)

FGF21 negatively affects long-term female fertility in mice
por: Moeckli, Beat, et al.
Publicado: (2022)

Liraglutide Increases FGF-21 Activity and Insulin Sensitivity in High Fat Diet and Adiponectin Knockdown Induced Insulin Resistance
por: Yang, Mengliu, et al.
Publicado: (2012)

Capparis spinosa improves the high fat diet-induced non-alcoholic steatohepatitis in rats: the possible role of FGF21
por: Akbari, Rasoul, et al.
Publicado: (2020)

FGF19 subfamily members: FGF19 and FGF21
por: Dolegowska, Katarzyna, et al.
Publicado: (2019)

Exercise ameliorates the FGF21–adiponectin axis impairment in diet-induced obese mice
por: Yang, Wenqi, et al.
Publicado: (2019)

FGF19 and FGF21 for the Treatment of NASH—Two Sides of the Same Coin? Differential and Overlapping Effects of FGF19 and FGF21 From Mice to Human
por: Henriksson, Emma, et al.
Publicado: (2020)

FGF19 and FGF21: In NASH we trust
por: Talukdar, Saswata, et al.
Publicado: (2020)

Hepatic PTP4A1 ameliorates high-fat diet-induced hepatosteatosis and hyperglycemia by the activation of the CREBH/FGF21 axis
por: Hwang, Byungtae, et al.
Publicado: (2023)

Oral Semaglutide
por: Bui, Vinh, et al.
Publicado: (2018)

Safety of Semaglutide
por: Smits, Mark M., et al.
Publicado: (2021)

Short-term cost-effectiveness of oral semaglutide for the treatment of type 2 diabetes mellitus in the United States
por: Cui, Jiayu, et al.
Publicado: (2021)

Hypocaloric Diet Prevents the Decrease in FGF21 Elicited by High Phosphorus Intake
por: Pineda, Carmen, et al.
Publicado: (2018)

Relationship Between the Serum FGF21 Level and Growth in Children of Short Stature
por: Lee, Yun Jeong, et al.
Publicado: (2023)

Lack of FGF21 promotes NASH-HCC transition via hepatocyte-TLR4-IL-17A signaling
por: Zheng, Qianqian, et al.
Publicado: (2020)

FGF21 Reduces Lipid Accumulation in Bovine Hepatocytes by Enhancing Lipid Oxidation and Reducing Lipogenesis via AMPK Signaling
por: Kong, Yezi, et al.
Publicado: (2022)

FGF21 and Cardiac Physiopathology
por: Planavila, Anna, et al.
Publicado: (2015)

Fundamentals of FGF19 & FGF21 Action In Vitro and In Vivo
por: Adams, Andrew C., et al.
Publicado: (2012)

Aging is associated with increased FGF21 levels but unaltered FGF21 responsiveness in adipose tissue
por: Villarroya, Joan, et al.
Publicado: (2018)

Maternal High-Fat Diet Alters the Characteristics of Astrocytes and Worsens the Outcome of Stroke in Rat Offspring, Which Improves After FGF21 Administration
por: Li, Yanxuan, et al.
Publicado: (2022)

Dietary Fat Quality in Normolipidic Diets Affects Hepatocyte’s Nuclear Phenotypes
por: Barbutti, Isabella, et al.
Publicado: (2020)

Fibroblast Growth Factor 21 (FGF21) in Human Cerebrospinal Fluid: Relationship With Plasma FGF21 and Body Adiposity
por: Tan, Bee K., et al.
Publicado: (2011)

A Short-Term High-Fat Diet Improved the Survival of Fat Grafts in Mice by Promoting Macrophage Infiltration and Angiogenesis
por: Niu, Xingtang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_a9n1lru442nju7b11m1mqrv4cn